Search for dissertations about: "post-mitotic"
Showing result 6 - 10 of 20 swedish dissertations containing the word post-mitotic.
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6. Chromosome dynamics and genomic instablity in neuroblastoma. Three genomic pillars: MYCN amplification, numerical and structural changes
Abstract : In this thesis, the main focus has been on the childhood cancer neuroblastoma, one of the most common and lethal childhood tumours. Neuroblastoma has througout the years continued to be a clinical and biological enigma. READ MORE
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7. Neruons; regulators of CNS inflammation
Abstract : Neurons have been neglected as cells with major immune regulatory function. Here, we present novel data demonstrating that neurons are highly immune competent and play crucial role in regulation of T cell response and CNS inflammation. READ MORE
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8. Lysosomal stability under the influence of oxidative stress and lipofuscin accumulation
Abstract : The lysosome is the cellular organelle responsible for degradation and recycling of macromolecules through hetero- and autophagocytosis. It is generally considered a stable organelle that breaks down only late during cellular degeneration. READ MORE
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9. Disassembly and reassembly of the nuclear pore complex
Abstract : The nuclear pore complexes (NPCs) are multiprotein communicative channels spanning the nuclear envelope. In higher eukaryotes NPCs reversibly disassemble during mitosis into distinct nucleoporin subcomplexes. Some cell types (e.g. READ MORE
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10. Deposition and Resolution of AA Amyloid
Abstract : Amyloidosis is a group of protein misfolding diseases characterized by extracellulardeposition of fibrillar protein aggregates. Today more than 25 different human amyloidogenicproteins have been identified, causing a variety of pathological conditions that includeAlzheimer’s disease, type 2 diabetes and prion diseases. READ MORE