Search for dissertations about: "post-translational modifications"

Showing result 21 - 25 of 118 swedish dissertations containing the words post-translational modifications.

  2. 21. Proximity Ligation Assay for High Performance Protein Analysis in Medicine

    Author : Gucci Jijuan Gu; Ulf Landegren; Thomas Joos; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein; post-translational modification; interactions; protein domain; western blotting; MARK; tau; AD; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : High quality reagents are preconditions for high performance protein analyses. But despite progress in some techniques, e.g. mass spectrometry, there is still a lack of affinity-based detection techniques with enhanced precision, specificity, and sensitivity. READ MORE

  4. 22. Proteomic analysis of Arabidopsis thaliana

    Author : Irene Granlund; Wolfgang Schröder; Birte Svensson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proteomic; speclust; post-translational modification; DIGE; plastocyanin; TL29; APX; thylakoid lumen; chloroplast stroma; Biochemistry; Biokemi;

    Abstract : A complete proteome analysis of the chloroplast stroma, using 2D-PAGE, from spinach and Arabidopsis was performed. To improve the identification of proteins a computer program named SPECLUST was used. READ MORE

  5. 23. Regulation of differentiation during the Giardia life cycle : An insight into the molecular control

    Author : Laura Rojas-López; Staffan Svärd; Marco Lalle; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; cell differentiation; encystation; histone post-translational modifications; host-parasite interaction;

    Abstract : Giardia intestinalis (syn. G. lamblia, G. duodenalis) is an intestinal protozoan parasite that causes diarrheal infections worldwide. READ MORE

  6. 24. Post-translational modifications of proteins in human breast cancer : proteomics studies of phosphorylation and nitration and implication of these PTMs in tumorigenesis

    Author : Min Jia; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breast cancer is the most common cancer in women. Even though improvements in diagnosis and treatment of breast cancer have been made, it is still the most common cause of cancer death in women. There is a great need to find biomarkers for early detection of the disease and novel drug targets to fight the cancer. READ MORE

  7. 25. Studies of Eosinophil Cationic Protein (ECP) in vivo and in vitro : Impact of Genetic and Posttranslational Modifications

    Author : Jenny Eriksson; Per Venge; Agneta Trulson; Ester Boix; Uppsala universitet; []
    Keywords : Biomedicine; Eosinophil granulocyte; granular protein; ECP; gene polymorphism; cytotoxicity; SELDI-TOF MS; glycosylation; molecular and functional heterogeneity; fibrosis; Biomedicin;

    Abstract : Eosinophil granulocytes are tissue dwelling leukocytes that are implicated in host defence, particularly against helminthic parasites; they also participate in most inflammatory disorders. Although eosinophils have important roles in host defence mechanisms, their actions can also be harmful to the host as in the allergic inflammation where lung epithelium is destructed due to the release of toxic granule proteins. READ MORE