Search for dissertations about: "potential malignant disorders"

Showing result 1 - 5 of 15 swedish dissertations containing the words potential malignant disorders.

2. 1. Ultraviolet light, autoimmune disorders and the etiology of malignant lymphomas

   Author : Karin Ekström Smedby; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Non-Hodgkin lymphoma; Hodgkin lymphoma; ultraviolet light; autoimmune disorders; rheumatoid arthritis; celiac disease; risk factors; cohort; case-control; epidemiology;

   Abstract : Malignant lymphomas constitute a clinically and morphologically diverse group of malignancies that may also differ etiologically. The incidence of the most common non-Hodgkin lymphomas (NHL) has increased dramatically worldwide during the past decades. READ MORE

4. 2. Malignant transformation of the colorectal mucosa in inflammatory bowel disease

   Author : Urban Sjöqvist; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Inflammatory bowel disease; ulcerative colitis; colorectal carcinoma; DNA-FCM; aneuploidy; dysplasia; Crohn s disease.;

   Abstract : Ulcerative colitis (UC) and Crohn's disease (CD) are disorders of unknown etiology, often referred to as inflammatory bowel diseases (IBD). The increased risk of colorectal cancer (CRC) in patients with longstanding, extensive colonic IBD is an important clinical problem. READ MORE

5. 3. Oral leukoplakia, human papillomavirus and cancer transformation : Factors related to human papillomavirus infection and cell proliferation

   Author : Jonas Sundberg; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; potentially malignant oral disorders; HPV; recurrence;

   Abstract : Oral leukoplakia (OL) is clinically diagnosed as a white oral lesion that cannot be scraped of or diagnosed as any other type of oral lesion. OL has the potential to transform into oral squamous cell carcinoma (OSCC). The gold standard treatment is a combination of surgical excision if possible, and surveillance. READ MORE

6. 4. Mechanisms and mediators of apoptosis : with special reference to hematological disorders

   Author : Bengt Fadeel; Karolinska Institutet; Karolinska Institutet; []
   Keywords : apoptosis; Bcl-2; caspases; chemotherapy; chronic granulomatous disease; familial hemophagocytic lymphohistiocytosis; Fas; homology-based modeling; neutrophils; phosphatidylserine; reactive oxygen species;

   Abstract : Life and death are inextricably entwined. Naturally occurring cell death or apoptosis is essential for the of homeostasis and serves to remove extraneous or dangerous cells in a swift and unobtrusive manner. work has demonstrated that such cell death is genetically regulated and transpires according to evolutionarily conserved pathways. READ MORE

7. 5. Neutrophil extracellular traps as potential therapeutic targets to prevent tumor-induced organ failure and metastasis

   Author : Melanie Herre; Anna-Karin Olsson; Jessica Cedervall; Peetra Magnusson; Benoit Ho-Tin-Noé; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutrophil extracellular traps; NETs; cancer; metastasis; inflammation; organ dysfunction; thrombosis; Oncology; Onkologi;

   Abstract : Cancer does not only affect surrounding tissues, but also leads to complications at distant sites. The reason for this is that tumors secrete factors and prime cells that travel through the body, making cancer a systemic disease. In fact, cancer death is mostly caused by systemic complications such as metastasis, organ failure or thrombosis. READ MORE