Search for dissertations about: "pravastatin"
Showing result 1 - 5 of 8 swedish dissertations containing the word pravastatin.
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1. Cell death in atherosclerosis
Abstract : Rupture of atherosclerotic lesions is recognized as the major cause of acute cerebrovascular and coronary syndromes. The characteristics of the typical vulnerable plaque include increased inflammatory cells at the shoulder region, a large lipid core, a thin fibrous cap with few collagen fibers and smooth muscle cells. READ MORE
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2. Alzheimer's Disease: The role of alpha1-antichymotrypsin-amyloid peptide (Abeta 1-42) interaction in the pathogenesis of Alzheimer's disease
Abstract : Alzheimer?s disease (AD) is an age-related, irreversible brain disorder that occurs gradually and results in memory loss, behavioural and personality changes. The disease is characterized by an abnormal accumulation of amyloid-beta (Ab) peptide in the extracellular space and the protein Tau within nerve cells of certain regions of the brain. READ MORE
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3. Platelet function in hyperlipoproteinemia and effects of lipid-lowering treatment
Abstract : Coronary atherosclerosis and thrombus formation on fissuring atherosclerotic plaques are key events in the development of coronary artery disease. Hyperlipoproteinemia induces atherosclerosis but may also exert direct prothrombotic effects via platelet activation. READ MORE
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4. On the regulation and effects of chronic inflammation in inflammatory bowel disease
Abstract : Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. READ MORE
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5. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients
Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE