Search for dissertations about: "pre-α-inhibitor"

Found 2 swedish dissertations containing the word pre-α-inhibitor.

  1. 1. Proteins of the Inter-α-inhibitor Family Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Aneta Kaczmarczyk; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. READ MORE

  2. 2. Intracellular processing of pre-a-inhibitor

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Maria Thuveson; Uppsala universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; pre-alpha-inhibitor; heavy chain 3; bikunin; intracellular processing; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Pre-α-inhibitor (PαI) is a plasma protein consisting of a 25 and a 75 kDa polypeptide: bikunin and heavy chain 3 (H3), respectively. Both these polypeptides are made by hepatocytes and while passing through the Golgi complex, bikunin, which carries a chondroitin sulfate chain, becomes covalently linked to the C-terminal amino acid residue of H3 via its polysaccharide. READ MORE