Search for dissertations about: "pre-treatment progression"

Showing result 1 - 5 of 13 swedish dissertations containing the words pre-treatment progression.

2. 1. Long-term treatment response, predictors and biochemical markers in Alzheimer’s disease

   Author : Åsa Wallin; Klinisk minnesforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; treatment response; cholinesterase inhibitor; CSF-biomarkers; pre-treatment progression; predictors; Alzheimer’s disease;

   Abstract : Alzheimer’s disease (AD) is clinically characterised by an insidious onset with progressive symptoms of memory impairment, dysphasia, dyspraxia, dygnosia and visuospatial difficulties. Degeneration of neurons in specific regions of the brain, formation of senile plaques and neurofibrillary changes are some of the neuropathological features of the disease. READ MORE

4. 2. Molecular markers for prediction of response and progression free survival to novel therapies in cutaneous malignant melanoma

   Author : Fernanda Costa Svedman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Drugs inhibiting the MAPK-pathway (MAPKi) and immune checkpoint inhibitors (ICI) have changed the clinical outcome of metastatic cutaneous malignant melanoma (CMM) in a significant way. Nonetheless, many patients have primary resistance or develop acquired resistance to these therapies within a relatively short period of time. READ MORE

5. 3. The influence of Al alloy microstructure on conversion coating formation

   Author : Salil Sainis; Caterina Zanella; Ehsan Ghassemali; Jönköping University; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aluminium alloys; cast Al-Si alloys; conversion coating treatment; cerium; localized deposition; surface pre-treatments; microstructure; SEM; FIB-SEM; AFM-SKPFM; aluminiumlegeringar; gjutna Al-Si legeringar; omvandlingsbeläggningar; cerium; lokaliserad deposition; ytförbehandlingar; microstruktur SEM; FIB-SEM; AFM-SKPFM;

   Abstract : The formation of conversion coatings based on Ce, trivalent Cr and Ti/Zr is triggered by the local pH increase at cathodic IM sites of the aluminium alloy microstructure. The pH gradient is created over the cathodic intermetallic (IM) sites of the microstructure and its intensity is influenced by their activity which depends on their chemical composition, their size, and spatial distribution. READ MORE

6. 4. In Search of Prognostic Factors in Grade 2 Gliomas

   Author : Dan Ribom; Tommy Bergenheim; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; low-grade glioma; positron emission tomography; platelet-derived growth factor receptor; mass spectrometry; alpha 2-HS glycoprotein; Neurovetenskap; Neurology; Neurologi; Neurology; Neurologi;

   Abstract : Grade 2 gliomas are malignant brain tumours affecting otherwise healthy adults. Although the long-term prognosis is poor, many patients are well and may have a high quality of life for several years. READ MORE

7. 5. Depression, coronary artery disease and change of lifestyle

   Author : Eva Söderman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Depression has been identified as a risk factor for the development of coronary artery disease (CAD) and has been associated with functional impairment and disability, poor outcome of lifestyle changes, incomplete and prolonged recovery, repeated coronary events, and mortality. Thus, there is substantial evidence that depression has a negative impact on CAD. READ MORE