Search for dissertations about: "precancerous"

Showing result 1 - 5 of 26 swedish dissertations containing the word precancerous.

2. 1. Cervical screening with primary HPV : from research to clinical effectiveness

   Author : Lovisa Bergengren; Gisela Helenius; Mats Karlsson; Matts Olovsson; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; screening; human papillomavirus HPV ; HPV prevalence; HPV genotypes; precancerous lesion; HSIL; self-sampling; postmenopausal women; health economy;

   Abstract : Organized cervical screening has greatly reduced the incidence of cervical cancer where implemented. Human papilloma virus (HPV) is the cause of cervical cancer, and in later years, convincing evidence has led to cervical screening with HPV as the primary method being implemented around the world. READ MORE

4. 2. Significance of Human Papillomavirus (HPV) Analysis for the Detection of Precancerous Cervical Lesions : Impact of Self Sampling

   Author : Karin Sanner; Matts Olovsson; Ingrid Wikström; Erik Wilander; Sven-Eric Olsson; Uppsala universitet; []
   Keywords : human papilloma virus; HPV; self-sampling; organized screening; cervical cancer screening; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : Cervical cancer is the second most common cancer, with about 500 000 new cases per year among women worldwide. With a well-organized screening programme the number of cases can be reduced by more than 50%. In spite of having such a screening programme there are still around 450 new cases yearly in Sweden. READ MORE

5. 3. Genital human papillomavirus (HPV) infections and their importance for the handling of precancerous lesions of the cervix uteri

   Author : Keng-Ling Chua; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: The development of cervical carcinoma, in a vast majority of cases, is closely related to infections with certain types of the human papillomavirus (HPV). The virus is supposed to exert its oncogenic effect mainly through interference with two proteins that are responsible for growth arrest as a response to DNA damage. READ MORE

6. 4. Epidemiological studies of Helicobacter pylori and its relation to cancer and precancerous lesions in the upper gastrointestinal tract

   Author : Maria Held; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Helicobacter pylori; atrophic gastritis; gastric cancer; esophagus cancer;

   Abstract : Helicobacter pylori infection is strongly associated with gastric cancer risk. The carcinogenic process is supposed to occur step by step, from a normal gastric epithelium via gastritis, atrophy, intestinal metaplasia to dysplasia. READ MORE

7. 5. Molecular markers reflecting malignant transformation and tumor progression

   Author : Patricia Stoltzfus; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Molecular markers; interphase fluorescence in situ hytidization; genetic diagnostic test; laminin-5 gamma2 chain; immunohistochemistry; precancerous lesions; invasiveness; breast cancer; cervical squamous cell carcinoma; tongue carcinoma; vulvar carcinoma;

   Abstract : The early detection of neoplastic lesions is most critical in the successful treatment of malignant disease. This thesis investigates molecular targets for an improved detection and diagnosis of cancer by exploring the value of interphase fluorescence in situ hybridization (FISH) to detect specific chromosomal aneuploidies and gene amplifications, and laminin-5 gamma2 chain expression detected by immunohistochemistry as a marker for invasiveness. READ MORE