Search for dissertations about: "precursor supply"

Showing result 1 - 5 of 26 swedish dissertations containing the words precursor supply.

  2. 1. Segmentation and differentiation in defence supply chain design : A dynamic purchasing portfolio model for defence procurement

    Author : Thomas Ekström; Per Hilletofth; Alastair Finlan; Per Skoglund; Lisa Ellram; Jönköping University; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; purchasing portfolio model; segmentation and differentiation; segmentation model; supply chain strategy; military logistics; defence procurement; defence supply chain design; modified Delphi study; portföljmodell; segmentering och differentiering; segmenterings-modell; försörjningsstrategi; militär logistik; försvarsanskaffning; utformning av militära försörjningskedjor; modifierad Delphistudie; Krigsvetenskap; War Studies;

    Abstract : An important priority in the current Swedish Defence Bill is to increase the operational warfighting capability of the Swedish Armed Forces, which has implications for the defence supply chain. A recent study suggested that the Swedish Armed Forces should use segmentation of supplies and differentiation of supply chains to enable an affordable supply chain design (SCD). READ MORE

  4. 2. Engineering central carbon metabolism with phosphoketolase pathways in Saccharomyces cerevisiae

    Author : John Hellgren; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; precursor supply; transcriptomics; sustainability; non-oxidative glycolysis; Carbon-conservation; metabolic engineering; platform strain; GATHCYC; proteomics;

    Abstract : We need more efficient biocatalysts to make sustainable microbial production of chemicals and fuels more profitable before they can replace petroleum-based sources. Rewiring the metabolic pathways in the biocatalysts to avoid the loss of carbon as CO2 can aid in improving product yields and thereby the profitability of the process. READ MORE

  5. 3. DNA precursor asymmetries, Mismatch Repair and their effect on mutation specificity

    Author : Robert Buckland; Andrei Chabes; Juan Méndez; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA Replication Fidelity; Mutations; dNTP pools; Mismatch Repair; Checkpoint; Ribonucleotide Reductase; Msh2; medicinsk biokemi; Medical Biochemistry; molekylärbiologi; Molecular Biology;

    Abstract : In order to build any structure, a good supply of materials, accurate workers and quality control are needed. This is even the case when constructing DNA, the so-called “Code of Life.” For a species to continue to exist, this DNA code must be copied with incredibly high accuracy when each and every cell replicates. READ MORE

  6. 4. Evaluation of precursor and cofactor engineering strategies influencing fatty acid metabolism in Saccharomyces cerevisiae

    Author : Alexandra Linda Bergman; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; metabolic engineering; fatty acids; oleochemicals; NADPH; Sustainability; phosphoketolase; acetyl-CoA; transcription factor;

    Abstract : If humanity is to reduce the rate of climate change, it is essential that our societies switch to a more sustainable production of fuels and chemicals, which in turn depends on technological development. Oleochemical production via microbial catalysts – such as the yeast Saccharomyces cerevisiae – can use a considerably broader range of renewable substrates compared to the conventional production processes. READ MORE

  7. 5. Physiology of Saccharomyces cerevisiae Producing Recombinant Insulin in Continuous Culture

    Author : Ali Kazemi Seresht; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; unfolded protein response; Keywords: heterologous protein production; prolonged chemostat; transcriptome; insulin analogue precursor; metabolic adaptation; URA3d; plasmid copy number; promoter truncation; high cell density cultivation; TPI1;

    Abstract : The yeast Saccharomyces cerevisiae has widely been used as a host for the production of heterologous proteins. High-level production of heterologous proteins is likely to impose a metabolic burden on the host cell and can thus affect various aspects of cellular physiology. READ MORE