Search for dissertations about: "prediktion"

Showing result 1 - 5 of 31 swedish dissertations containing the word prediktion.

  1. 1. A multivariate approach to characterization of drug-like molecules, proteins and the interactions between them

    University dissertation from Umeå : Kemi

    Author : Anton Lindström; Anna Linusson; Fredrik Almqvist; Anders Karlén; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; binding affinity; prediction; CAMD; principal component analysis PCA ; partial least squares projections to latent structures PLS ; MM-GB-SA; MM-PB-SA; docking; geometry optimization; protein secondary structure characterization; implicit solvent; generalized-Born; Poisson-Boltzmann; molecular mechanics MM ; drug discovery; bindningsaffinitet; prediktion; dockning; geometrioptimering; sekundärstruktur; matematisk vattenmodel; generalized-Born; Poisson-Boltzmann; molekylmekanik MM ; läkemedelsdesign; principal komponent analys PCA ; partial least squares projections to latent structures PLS ; MM-GB-SA; MM-PB-SA; NATURAL SCIENCES Chemistry Other chemistry; NATURVETENSKAP Kemi Övrig kemi;

    Abstract : En sjukdom kan många gånger härledas till en kaskadereaktion mellan proteiner, co-faktorer och substrat. Denna kaskadreaktion blir många gånger målet för att behandla sjukdomen med läkemedel. För att designa nya läkemedelsmoleyler används vanligen datorbaserade verktyg. READ MORE

  2. 2. Ground vibrations due to pile and sheet pile driving influencing factors, predictions and measurements

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Fanny Deckner; Staffan Hintze; Kenneth Viking; Sigurdur Erlingsson; [2013]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ground vibration; pile; sheet pile; prediction; markvibrationer; påle; spont; prediktion;

    Abstract : Ground vibrations due to pile driving are part of a complex process. Vibration is generated from the pile driver to the pile. As the pile interacts with the surrounding soil, vibrations are transferred at the pile-soil interface. The vibration propagates through the ground and interacts with structures, both above ground and underground. READ MORE

  3. 3. On protein structure, function and modularity from an evolutionary perspective

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Robert Pilstål; Björn Wallner; Maria Sunnerhagen; Mauno Vihinen; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; structure; biology; intrinsical; disorder; protein; sequence; evolution; mutation; epistasis; function; allostery; dynamics; simulation; prediction; graph; network; bioinformatik; struktur; biologi; strukturbiologi; intrinsiellt; oordnad; protein; sekvens; evolution; mutation; epistasis; funktion; allosteri; dynamik; simulation; prediktion; graf; nätverk;

    Abstract : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. READ MORE

  4. 4. On sepsis - epidemiology, prediction and diagnostics

    University dissertation from Lund University, Faculty of Medicine

    Author : Lisa Mellhammar; [2020]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; Epidemiologi; Early Warning Score; Bacteremia;

    Abstract : The overall aims of this thesis were to improve prediction, diagnostics and knowledge on epidemiology of sepsis. In paper I, we developed and evaluated an integrated platform for rapid analysis of sepsis-causing organisms directly from blood samples. READ MORE

  5. 5. Improved diagnosis and prediction of community-acquired pneumonia

    University dissertation from Umeå : Umeå universitet

    Author : Alicia Edin; Anders F. Johansson; Anders Sjöstedt; Annika Allard; Thomas Schön; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Community-acquired pneumonia; infection; diagnosis; qPCR; metabolites; metabolomics;

    Abstract : Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality worldwide. Although there is wide variation in the microbial etiology, CAP may manifest with similar symptoms, making institution of proper treatment challenging. READ MORE