Search for dissertations about: "preeclampsia"
Showing result 16 - 20 of 92 swedish dissertations containing the word preeclampsia.
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16. The role of natural killer cells and inflammatory mediators in preeclamptic pregnancies
Abstract : The maternal immune system must be able to adjust during pregnancy and accept the foetus that expresses paternal antigens. These changes are found both in placenta and circulation, including a mild inflammatory response. NK cells are abundant during the early part of pregnancy in placenta and are thought to be important for placental development. READ MORE
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17. Aspects of Gestational Diabetes : Screening System, Maternal and Fetal Complications
Abstract : The appropriateness of universal screening for gestational diabetes mellitus (GDM) has been strongly questioned, since it does not satisfy ethical principles for screening. The aims of these studies were to determine the prevalence of GDM, expressed in terms of impaired glucose tolerance (IGT) and diabetes mellitus (DM), to evaluate different screening models using traditional anamnestic risk factors and repeated random B-glucose, to determine whether GDM increases risks for maternal complications such as preeclampsia, and to determine whether IGT during pregnancy, if left untreated, is associated with increased maternal or neonatal morbidity. READ MORE
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18. A1M: a heme and radical binding protein. A study on structure, function and mechanisms
Abstract : This thesis describes functional and structural studies of the human protein α1-microglobulin (A1M), an evolutionarily well-conserved 26 kDa plasma and tissue protein mainly synthesized in the liver. A1M belongs to the lipocalin protein family. Lipocalins share a very similar structur, an 8-stranded β-barrel forming a hydrophobic pocket. READ MORE
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19. Monoamine transporters in female human reproduction
Abstract : The present study explored the gene and protein expression of the monoamine transporters in human endometrium throughout the menstrual cycle, in early decidua and in placentas from normal as well as preeclamptic pregnancies using in-situ hybridization, real time-PCR, immunohistochemistry and primary tissue cultures. Four distinguishable patterns were observed in the endometrium over the menstrual cycle: (1) epithelial expression of norepinephrine transporter (NET) mRNA, (2) Stromal co- expression of vesicular monoamine transporter 2 (VMAT2) and plasma membrane monoamine transporter (PMAT) mRNAs with maximal intensity in the proliferative phase; (3) increasing epithelial expression of VMAT2 mRNA with a maximum in the late secretory phase; (4) stromal expression of extra-neuronal monoamine transporter (EMT) mRNA with a peak in the early secretory phase. READ MORE
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20. Exposure to air pollution during pregnancy and health risks for mother and child
Abstract : We had in the present thesis the unique possibility to use, in a socio-economically relatively homogenous population, high quality registry information on a population-based birth cohort (84 039 births during the period 1999-2005) in Scania (Skåne), the most Southern county of Sweden. The aim of the thesis was to investigate whether exposure to air pollution, in an area of low-levels exposures, during different periods of the pregnancy was associated with birth outcomes, pregnancy complications and risk of the child to develop type I diabetes (T1D). READ MORE
