Search for dissertations about: "pregnancy hypothyroidism"

Showing result 1 - 5 of 9 swedish dissertations containing the words pregnancy hypothyroidism.

  2. 1. Hypothyroidism and Pregnancy

    Author : Michaela Granfors; Anna-Karin Wikström; Inger Sundström-Poromaa; Helena Åkerud; Ulla Feldt-Rasmussen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phosphodiesterase 8B; recurrent miscarriage; single nucleotide polymorphism; thyroid; guidelines; hypothyroidism; pregnancy; survey; thyroid testing; screening; iodine; iodine deficiency; median urinary iodine concentration; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Hypothyroidism is a common endocrine disorder affecting women of reproductive age. On a global level, iodine deficiency is still the most common cause of hypothyroidism. Also genetic variations, in particular SNP rs4704397 in the PDE8B gene, are responsible for a significant proportion of TSH variations. READ MORE

  4. 2. Endocrine and paracrine factors related to pregnancy and infertility

    Author : Frida Hosseini Akram; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Unexplained infertility, one of the common gynecological disorders, affecting 10 to 15 % of women worldwide. Recurrent pregnancy loss affects approximately 1 to 3 % of pregnant women with an unknown etiology in 50 % of cases. Endocrine dysfunctions, including thyroid dysfunction, are one of the related factors to female reproductive disturbances. READ MORE

  5. 3. Hypothyroidism caused by a mutant thyroid hormone receptor alpha1 : consequences for development and physiology

    Author : Maria Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lack of sufficient thyroid hormone during pregnancy and early postnatal development results in profound mental retardation and motor deficits whereas altered thyroid status in the adult is associated with disturbed metabolic homeostasis and impaired cardiac function. Thyroid hormone mediates its effects through the distinct thyroid hormone receptors (TR) TRalpha1 and TRbeta1-2, which are ligand-modulated transcription factors that regulate gene expression both in the presence and absence of hormone. READ MORE

  6. 4. Membrane transport of triiodothyronine : With particular reference to erythrocytes in health and disease

    Author : Ann-Charlotte Holm; Nils Nordén; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Cellular T3 uptake was studied in three human cell systems, i.e. cultured lymphocytes, erythrocytes and erythrocyte membrane vesicles. READ MORE

  7. 5. Register-based studies of delivery outcome after maternal use of some common drugs

    Author : Birgitta Norstedt Wikner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis aimed to study neonatal outcome including the presence of congenital malformations and to describe maternal characteristics for women using some common drugs during pregnancy. Drugs used in one benign condition (nausea and vomiting) and one chronic disease (hypothyroidism) and the CNS-active drugs benzodiazepines and hypnotic benzodiazepine receptor agonists were selected. READ MORE