Search for dissertations about: "prekallikrein"

Found 4 swedish dissertations containing the word prekallikrein.

  2. 1. The kallikrein-kinin system in primary hypertension : dynamics of circulating components of the kallikrein-kinin system in relation to the renin-angiotensin-aldosterone system

    Author : K. Peter Öhman; Linköpings universitet; []
    Keywords : aldosterone; angiotensin Il; blood pressure; human; prekallikrein; renin; tissue kallikrein; MEDICINE; MEDICIN;

    Abstract : Kinins are potent vasodilatory and blood pressure lowering peptides, with additional effects on renal handling of electrolytes and water. The kallikrein-kinin system consists of two separate entities, one confined to the circulation and the other to both tissues and the circulation. READ MORE

  4. 2. Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases

    Author : Jenny Björkqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions. READ MORE

  5. 3. Intestinal Ischemia and Reperfusion Injury - Pathophysiology as basis for novel treatment

    Author : Zhengwu Sun; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; organ dysfunction; epithelium; endothelium; adhesion molecules; cytokines; protease inhibitor; Intestine; barrier; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : Intestinal ischemia and reperfusion (I/R) is not infrequent in the clinical situation and the intestinal barrier plays an important role in gut barrier function, preventing not at least septic complications and potentially the development of the multiple organ dysfunction syndrome. Mechanisms of intestinal I/R induced gut epithelial and endothelial barrier dysfunction and remote organ dysfunction, as well as potential preventive and therapeutic modes of management were evaluated in the rat. READ MORE

  6. 4. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function

    Author : Narinder Gautam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Inflammation; leukocyte extravasation; endothelial cells; vascular permeability; plasma leakage integrin signaling; heparin binding protein; contact phase; bradykinin.;

    Abstract : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. READ MORE