Search for dissertations about: "pressure vessels"

Showing result 1 - 5 of 108 swedish dissertations containing the words pressure vessels.

  1. 1. Regulation of vascular function by fluid mechanical forces. Development of a new vascular experimental platform for integrative physiological and molecular biological studies of living conduit vessels

    Author : Li-Ming Gan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perfusion model; endothelium; smooth muscle cells; shear stress; pressure; nitric oxide; endothelin-1; vascular endothelial growth factor; c-jun; c-fos; real-time PCR; NO probe.;

    Abstract : The vascular endothelium is a multifunctional interface between blood flow and target organs and is continuously exposed to fluid mechanical forces such as shear stress, compressive, and tensile forces. Both in vivo and in vitro data indicate that biomechanical forces exert important modulating effects on key vascular functions. READ MORE

  2. 2. Thermo-mechanical Assessment of Reactor Pressure Vessels of Light Water Reactors During Severe Accidents

    Author : Hongdi Wang; Walter Villanueva; Sevostian Bechta; Weimin Ma; Artem Kulachenko; Michael Fitzpatrick; KTH; []
    Keywords : Severe accident scenario; reactor pressure vessel; in-vessel melt retention; failure analysis; finite element analysis; validations; Scenario för svåra haverier; reaktortank; in-vessel retention; feleffektsanalys; Finite Element Analyser; validering; Physics; Fysik;

    Abstract : The reactor pressure vessel (RPV) is one of the crucial safety barriers designed to isolate the reactor core, safeguarding against potential radioactive releases into the environment during a severe accident. The assessment of RPV behaviour and its failure is necessary to predict the characteristics of melt release into the reactor pit and succeeding ex-vessel accident progression. READ MORE

  3. 3. Distensibility in Arteries, Arterioles and Veins in Humans : Adaptation to Intermittent or Prolonged Change in Regional Intravascular Pressure

    Author : Roger Kölegård; Ola Eiken; Toste Länne; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; arterial stiffness; venous distensibility; venous flow characteristics; bedrest; pressure training; Physiology; Fysiologi;

    Abstract : The present series of in vivo experiments in healthy subjects, were performed to investigate wall stiffness in peripheral vessels and how this modality adapts to iterative increments or sustained reductions in local intravascular pressures. Vascular stiffness was measured as changes in arterial and venous diameters, and in arterial flow, during graded increments in distending pressures in the vasculature of an arm or a lower leg. READ MORE

  4. 4. Experimental studies of the regulations of synthesis and release of tissue-type plasminogen activator from vascular endothelium

    Author : Lena Selin Sjögren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tissue-type plasminogen activator; endothelium; fluid mechanical forces; shear stress; pressure; immunohistochemistry; gene expression;

    Abstract : The fibrinolytic system has several important functions and one crucial function is the prevention and removal of fibrin deposits in blood vessels. Tissue-type plasminogen activator (t-PA) plays a key role in this process, and in vitro data suggest that an acute release of t-PA is induced as a thromboprotective response whenever clotting mechanisms are initiated. READ MORE

  5. 5. Effects of Ischaemia on the Neuroretina and Retinal Blood Vessels

    Author : Bodil Gesslein; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein kinase C; tumor necrosis factor; mitogen-activated protein kinases; pig; blood vessels; mfERG; Retinal ischaemia; vascular endothelial growth factor; hypoxia-inducible factor;

    Abstract : Identification of the intracellular signal transduction pathways activated in retinal ischaemia may be important in revealing novel pharmacological targets. The retinal blood vessels are key organs in circulatory failure, and in this work the retinal vasculature was therefore examined separately from the neuroretina. READ MORE