Search for dissertations about: "prima"
Showing result 1 - 5 of 50 swedish dissertations containing the word prima.
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1. Development of a new service-oriented modelling method for information systems analysis and design
Abstract : This thesis presents a new modelling method for information systems analysis and design, where the concept of service and the principles of service orientation are used for integrated modelling and reasoning about information systems architectures across organisational and technical systems boundaries. The concept of service enables cohesion of the intersubjective and objective modelling traditions by using a single type of diagram that facilitates detection of semantic inconsistency, incompleteness, ambiguity and discontinuity between the static and dynamic aspects of information systems specifications. READ MORE
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2. Mutant p53 reactivation by prima-1 : molecular mechanism and biological effects
Abstract : Cancer has become one of the leading causes of death worldwide. It is now clear that tumors arise due to the malfunction of a number of genes, thus emphasising the importance of targeted therapies directed to crucial types of genetic alterations. READ MORE
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3. Early Determination of Arbitral Jurisdiction : Balancing efficacy, efficiency, and legitimacy of arbitration
Abstract : This dissertation examines the timing of judicial determination of jurisdictional disputes in the presence of an arbitration agreement. The analysis focuses on Article 8(1) of the UNCITRAL Model Law on International Commercial Arbitration (and Article II(3) of the New York Convention on the Recognition and Enforcement of Foreign Arbitral Awards). READ MORE
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4. Rescue of mutant p53 family members by the low molecular weight compound PRIMA-1MET/ APR-246
Abstract : The tumor suppressor p53, guardian of the genome, is induced and activated by cellular stress signals such as DNA damage, hypoxia and activation of oncogenes. p53 upregulates downstream target genes, that are involved in cell cycle arrest, senescence, apoptosis, etc. Mutations in p53 occur frequently (around 50%) in many human tumors. READ MORE
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5. The Prima Porta Garden Archaeological Project. Terra sigillata from the Villa of Livia, Rome. Consumption and discard in the early Principate
Abstract : This study examines a corpus of Italian sigillata from the Villa of Livia outside Rome, and presents the excavations during which it was found. Most of the material stems from archaeologically secure contexts, a refuse tip and dump dating to the late Augustan and Neronian periods respectively. READ MORE