Search for dissertations about: "primary HIV-1 infection"
Showing result 1 - 5 of 57 swedish dissertations containing the words primary HIV-1 infection.
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1. HIV-1 infection of the central nervous system. Markers of pathogenesis and antiretroviral treatment effects
Abstract : Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS) early in the course of infection and either directly or through opportunistic infections causes a spectrum of neurological complications. The most severe manifestation of HIV-1 CNS infection is AIDS Dementia Complex (ADC), which occurs in approximately 20% of untreated patients with AIDS. READ MORE
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2. Development of novel molecular and microfluidics tools for identification and characterization of latent HIV-1 reservoir
Abstract : The existence of latent HIV-1 reservoir (LR) in all HIV-1 infected patients serves as a major obstacle to completely cure HIV-1 infection. However, up to now there is still no available assay that provides an accurate measurement of the reservoir size. READ MORE
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3. Primary HIV-1 infection : diagnostic, prognostic, and therapeutic aspects
Abstract : Primary HIV-1 infection (PHI) is usually defined as a mononucleosis-like illness associated with seroconversion to HIV. In earlier studies using 1st generation antibody tests, the duration of the 'window period' from infection to detection of specific HIV-antibodies, could be 2 to 3 months, or longer. READ MORE
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4. HIV-1 envelope protein gp120. Glycovirology of the V3 loop
Abstract : The human immunodeficiency virus type 1 (HIV-1) infection usually is lethal as a consequence of the acquired immunodeficiency syndrome (AIDS). HIV-1 is an enveloped virus and the trimeric envelope glycoprotein complex, gp120/gp41, is responsible for binding of the virus both to the primary cellular receptor CD4 and the coreceptors, CXCR4 and CCR5. READ MORE
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5. Aspects of immune activation in HIV-1 infection
Abstract : Abnormal immune system activation is central in HIV-1 pathogenesis leading to CD4+ T-cell depletion and inappropriate immune responses. Disease stage and HIV load strongly correlate with the immune activation level which decreases under antiretroviral therapy (ART). READ MORE