Search for dissertations about: "primary cell culture"

Showing result 1 - 5 of 171 swedish dissertations containing the words primary cell culture.

  1. 1. Aiway Mucins: experimental models for studies of secretions

    Author : Naila Svitacheva; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystic fibrosis; bovine trachea; radiolabelling; cell line; primary cell culture; organ culture; mucus; mucin; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Mucins are essential components of the mucosal barrier. The complexity of the airway mucosal barrier is reflected in the lack of specific treatments to block mucin hypersecretion associated with several respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis. READ MORE

  2. 2. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers

    Author : Staffan Tavelin; Per Artursson; Staffan Tavelin; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; intestinal epithelium; tight junctions; cell culture; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Abstract : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. READ MORE

  3. 3. In vitro Studies of β-cell Death and Survival. Modulation by Adenoviral Vectors and Bcl-2 Overexpression

    Author : Andreea Roxana Barbu; Nils Welsh; Decio Eiziric; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; β-cell; cytokine; mitochondrial membrane potential; Bcl-2; Adenoviral vector; Adenovirus; IFN-α; Diabetes; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : Type 1 diabetes is a multifactorial disease resulting from the selective destruction of insulin-producing β-cells within the pancreatic islets of Langerhans. The mechanisms of β-cell death are not fully understood but cytokines are important mediators of this process. READ MORE

  4. 4. Cell therapy for denervated tissue

    Author : Roine El-Habta; Ludvig J. Backman; Paul J. Kingham; Patrik Danielson; António Salgado; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue-derived stem cell; cell therapy; denervation; differentiation; myoblast; peripheral nerve injury; proliferation; regeneration; skeletal muscle; stromal vascular fraction; survival; tendon; cellforskning; cell research; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Background: Peripheral nerve injury results in denervation of tendons and muscles. The biology of denervated muscle has been well studied but little is known about the associated tendons. READ MORE

  5. 5. Sugar-modulated gene expression and cell division in cell culture and seedlings of A. thaliana

    Author : Sabine Kunz; Leszek A. Kleczkowski; Alison Smith; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis thaliana; carbohydrates; cell culture; cell division; gene expression; homeostasis; live cell imaging; sugar-signals; sugar-analogues; Physiological Botany; fysiologisk botanik;

    Abstract : Throughout their life cycle, plants adjust growth in response to their developmental and environmental situation within the limits of their energetic capacities. This capacity is defined by the local sugar availability, which is constantly modulated through synthesis, transport and consumption of sugar. READ MORE