Search for dissertations about: "primary cell culture"

Showing result 11 - 15 of 186 swedish dissertations containing the words primary cell culture.

2. 11. Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease

   Author : Paul O'Callaghan; Xiao Zhang; Lars Lannfelt; Jeremy Turnbull; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; amyloidosis; amyloid-β; apolipoprotein E; astrocytes; glia; heparanase; heparan sulfate; heparan sulfate proteoglycans; microglia; neuroinflammation; Geriatrics; Geriatrik; Cellforskning; Cell Research; Neuroscience; Neurovetenskap; Pathology; Patologi;

   Abstract : Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglycans (HSPGs). READ MORE

4. 12. The Enteric Nervous System, Plasticity and Survival

   Author : Katarina Sandgren; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; Nitric oxide synthase; Neuropeptides; Neuronal survival; Lethal spotted mice; Interstitial cells of Cajal; Hirschsprung s disease; Cell cultures; Enteric nervous system; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Abstract : The thesis deals with plasticity in terms of neurotransmitter expression and survival of neurons in the adult enteric nervous system (ENS). Several motility disorders have been suggested to originate in developmental defects, neurodegeneration, or insufficient innervation by the ENS. READ MORE

5. 13. A Study of Eosinophils – From the Human Thymus to Eosinophilic Esophagitis

   Author : Sofie Albinsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Eosinophil; Eosinophilic esophagitis; Galectin-10; Human; Patient-reported outcome; T cell; Thymocyte; Thymus;

   Abstract : Eosinophils are cells of the innate immune system. They primarily reside within tissues and are most numerous in the gastrointestinal tract but are absent from the healthy esophagus. During the inflammatory disease eosinophilic esophagitis, eosinophils infiltrate the esophagus but their function is unknown. READ MORE

6. 14. Neuropeptide and catecholamine effects on tenocytes in tendinosis development : studies on two model systems with focus on proliferation and apoptosis

   Author : Ludvig Backman; Patrik Danielson; Malcolm Collins; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; substance P; neurotransmitter; tendinopathy; overuse injury; rabbit; tendon cell; Achilles tendon;

   Abstract : Background: Achilles tendinopathy is a common clinical syndrome of chronic Achilles tendon pain combined with thickening of the tendon and impaired tendon function. Tendinopathy is often, but not always, induced by mechanical overload, and is frequently accompanied by abnormalities at the tissue level, such as hypercellularity and angiogenesis, in which case the condition is called tendinosis. READ MORE

7. 15. Paracrine and autocrine functions of PDGF in malignant disease

   Author : Tobias Sjöblom; Lars Holmgren; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi; Cell biology; Cellbiologi; Molecular Biology; molekylärbiologi;

   Abstract : Growth factors and their receptors are frequently activated by mutations in human cancer. Platelet-derived growth factor (PDGF)-B and its tyrosine kinase receptor, the PDGF β-receptor, have been implicated in autocrine transformation as well as paracrine stimulation of tumor growth. READ MORE