Search for dissertations about: "primary melanoma"

Showing result 1 - 5 of 69 swedish dissertations containing the words primary melanoma.

2. 1. Genomic analysis of primary and metastatic malignant melanoma

   Author : Katja Harbst; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; next-generation sequencing; microarray; progression; molecular grade; subtype; melanoma;

   Abstract : “Cutaneous melanoma is a most unpredictable lesion” wrote Alexander Breslow in 1970. He was one of the first to predict outcome in melanoma patients, based on the thickness of the primary tumor, and today this parameter bears his name and remains the main prognostic factor in melanoma. READ MORE

4. 2. Cutaneous melanoma in children and adolescents and aspects of naevus phenotype in melanoma risk assessment

   Author : Pia Karlsson; Inger Rosdahl; Johan Hansson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melanoma; naevus; childhood; adolescence; prevention; epidemiology; Dermatology and venerology; Dermatologi och venerologi;

   Abstract : Cutaneous malignant melanoma (CMM) is one of the most rapidly increasing cancers in the Swedish population. The aetiology of melanoma is a complex interplay between genetics, host characteristics and environmental factors. READ MORE

5. 3. Clinical aspects of molecular profiles in metastatic malignant melanoma

   Author : Henrik Ekedahl; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanom; Prognos; BRAF; TERT; Genuttryck; Next generation sequencing; Melanoma; Prognosis; BRAF; TERT; Gene Expression; Next generation sequencing;

   Abstract : Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. READ MORE

6. 4. Cutaneous malignant melanoma : body site, sun exposure, genetic factors and prognosis

   Author : Daniela Gordon; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Melanoma;

   Abstract : Background: The interplay between tumor site, ultraviolet radiation (UVR) exposure, genetic factors and various epidemiological parameters of cutaneous melanoma is complex. In this thesis, we aimed to investigate the impact of detailed body site of the primary tumor beyond the conventional and strictly anatomic division of the head-neck, trunk, upper- and lower extremities, focusing on body site division according to UVR exposure patterns in relation to risk, outcome and other factors. READ MORE

7. 5. Malignant melanoma-Risk factors and the CDKN2A mutation in relation to phenotypes and other cancers

   Author : Kari Nielsen; Lund Dermatologi och venereologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinically atypical nevus; nevus; CDKN2A; melanoma; risk factors; sunbed; UVR;

   Abstract : Background: Cutaneous malignant melanoma (CMM) is an increasingly common cancer in fair-skinned people. The purpose of this thesis was to study high-risk patients with multiple tumours including a CMM, high-risk families with the unique Swedish germline mutation in CDKN2A(113insArg), as well as study risk factors for CMM in women. READ MORE