Search for dissertations about: "primer"
Showing result 1 - 5 of 107 swedish dissertations containing the word primer.
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1. Molecular insights into primer removal during mtDNA replication
Abstract : Mitochondria are vital for cell survival, and the primary producers of ATP, the energy currency used for various metabolic processes. Mitochondria are unique from other cellular compartments because they have their own genomes of circular small double-stranded DNA (mtDNA) of approximately 16. READ MORE
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2. Structural and biochemical basis for the high fidelity and processivity of DNA polymerase ε
Abstract : DNA polymerase epsilon (Pol ε) is a multi-subunit B-family DNA polymerase that is involved in leading strand DNA replication in eukaryotes. DNA Pol ε in yeast consists of four subunits, Pol2, Dpb2, Dpb3, and Dpb4. Pol2 is the catalytic subunit and Dpb2, Dpb3, and Dpb4 are the accessory subunits. READ MORE
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3. Allogeneic dendritic cells as adjuvants in cancer immunotherapy
Abstract : In recent years, immunotherapeutic approaches have achieved remarkable successes through checkpoint blockade antibodies, advances in the use of chimeric antigen receptor (CAR) T cells and new insights into the immunosuppressive role of the tumor microenvironment (TME). Through the advances, the role of cancer vaccines based on ex vivo manipulated autologous dendritic cells (DC) has been challenged. READ MORE
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4. Chemical communication in mating shore crabs Carcinus maenas
Abstract : Locating and evaluating a suitable partner for mating is one of the most important events in any sexually reproducing organism. To achieve this, an animal must be able to locate its partner over both long and short distances, and finally evoke the proper mating behaviour. READ MORE
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5. Selection of antigens for antibody-based proteomics
Abstract : The human genome is predicted to contain ~20,500 protein-coding genes. The encoded proteins are the key players in the body, but the functions and localizations of most proteins are still unknown. READ MORE