Search for dissertations about: "principal komponent analys PCA"

Found 3 swedish dissertations containing the words principal komponent analys PCA.

  1. 1. A multivariate approach to characterization of drug-like molecules, proteins and the interactions between them

    University dissertation from Umeå : Kemi

    Author : Anton Lindström; Anna Linusson; Fredrik Almqvist; Anders Karlén; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; binding affinity; prediction; CAMD; principal component analysis PCA ; partial least squares projections to latent structures PLS ; MM-GB-SA; MM-PB-SA; docking; geometry optimization; protein secondary structure characterization; implicit solvent; generalized-Born; Poisson-Boltzmann; molecular mechanics MM ; drug discovery; bindningsaffinitet; prediktion; dockning; geometrioptimering; sekundärstruktur; matematisk vattenmodel; generalized-Born; Poisson-Boltzmann; molekylmekanik MM ; läkemedelsdesign; principal komponent analys PCA ; partial least squares projections to latent structures PLS ; MM-GB-SA; MM-PB-SA; NATURAL SCIENCES Chemistry Other chemistry; NATURVETENSKAP Kemi Övrig kemi;

    Abstract : En sjukdom kan många gånger härledas till en kaskadereaktion mellan proteiner, co-faktorer och substrat. Denna kaskadreaktion blir många gånger målet för att behandla sjukdomen med läkemedel. För att designa nya läkemedelsmoleyler används vanligen datorbaserade verktyg. READ MORE

  2. 2. Bayesian methods for sparse and low-rank matrix problems

    University dissertation from KTH Royal Institute of Technology

    Author : Martin Sundin; Magnus Jansson; Saikat Chatterjee; Yoram Bresler; [2016]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electrical Engineering; Elektro- och systemteknik;

    Abstract : Many scientific and engineering problems require us to process measurements and data in order to extract information. Since we base decisions on information,it is important to design accurate and efficient processing algorithms. This is often done by modeling the signal of interest and the noise in the problem. READ MORE

  3. 3. Multivariate data analysis of metabolomic multi-tissue samples

    University dissertation from Umeå : Umeå universitet

    Author : Frida Torell; Johan Trygg; Torbjörn Lundstedt; Thomas Moritz; Kate Bennett; Michal Daszykowski; [2020]

    Abstract : Multi-tissue metabolomics involves characterisation of the metabolome of several tissue types. The metabolome consists of small chemical entities of low molecular weight called metabolites, which are constantly produced and interchanged through a vast variety of biochemical reactions occurring throughout living organisms. READ MORE