Search for dissertations about: "pro-inflammatory"

Showing result 11 - 15 of 584 swedish dissertations containing the word pro-inflammatory.

  2. 11. MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia

    Author : Aida Maddahi; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitogen activated protein kinase; iNOS; Matrix metalloproteinases; IL-1ß; IL-6; TNF-α; Inflammation; Subarachnoid hemorrhage; Middle cerebral artery occlusion;

    Abstract : INTRODUCTION Stroke is a serious neurological disease which may lead to death and severe disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. READ MORE

  4. 12. Role of pro-inflammatory S100A9 protein in amyloid-neuroinflammatory cascade in Alzheimer’s disease and traumatic brain injury

    Author : Chao Wang; Ludmilla Morozova-Roche; Jonathan Gilthorpe; Øyvind Halskau; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100A9; Aβ; Alzheimer s disease; Traumatic brain injury; Amyloid; Neuroinflammatory; medicinsk biokemi; Medical Biochemistry;

    Abstract : Background Traumatic brain injury (TBI) is a complex disease with a spectrum of symptoms and disabilities. Over the past decade TBI has become the focus of research due to growing epidemiological and clinical evidences that TBI incidences are strong risk factors for Alzheimer’s disease (AD). READ MORE

  5. 13. Perinatal brain injury - markers and mediators. Non-protein-bound iron and pro-inflammatory cytokines in newborn infants and neonatal pigs

    Author : Karin Sävman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asphyxia; hypoxia; posthemorrhagic ventricular dilatation; preterm; newborn; perinatal; brain; cerebrospinal fluid; cytokines; IL-1ß; IL-6; IL-8; TNF-a; non-protein-bound-iron;

    Abstract : Two groups of newborn infants have an increased risk for perinatal brain injury; preterm infants and term infants subjected to birth asphyxia. Experimental studies indicate that hypoxic-ischemic insults in the perinatal period initiate a secondary neurotoxic cascade including formation of toxic reactive oxygen species as well as an inflammatory response with elevated levels of potentially neurotoxic cytokines. READ MORE

  6. 14. Immune mechanisms in atherosclerotic vascular disease

    Author : Jasmina Cvetkovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherosclerosis; rheumatoid arthritis; stroke; autoantibodies; pro-inflammatory cytokines;

    Abstract : Atherosclerosis has been categorized as an inflammatory disorder, with similar chronic inflammatory conditions found in rheumatoid arthritis. It entails an unregulated accumulation of lipids in the vessel wall, which leads to the development of cardiovascular diseases. READ MORE

  7. 15. Cytokines and cytokine-directed intervention in experimental arthritis

    Author : Karin Palmblad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : pro-inflammatory cytokines; collagen-induced arthritis; CNI-1493; HMG-1;

    Abstract : Rheumatoid arthritis (RA) is a common chronic autoimmune and inflammatory disease. Although the etiology of RA remains unknown, a general understanding of the pathogenesis is steadily increasing. The macrophage products tumor necrosis factor (TNF) and interleukin 1 (IL-1) are recognized as pivotal mediators in the arthritic process. READ MORE