Search for dissertations about: "pro-inflammatory"

Showing result 6 - 10 of 584 swedish dissertations containing the word pro-inflammatory.

  1. 6. Severe cerebral emergency : aspects of treatment and outcome in the intensive care patient

    Author : Marie Rodling Wahlström; Silvana Naredi; Sven-Erik Gisvold; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; severe traumatic brain injury; intracranial pressure-targeted therapy; albumin; prostacyclin; endothelial dysfunction; pro-inflammatory cytokines; subarachnoid haemorrhage; asymmetric dimethylarginine; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anaesthesiology; anestesiologi;

    Abstract : Severe Traumatic Brain Injury (TBI) and aneurysmal Subarachnoid Hemorrhage (SAH) are severe cerebral emergencies. They are common reasons for extensive morbidity and mortality in young people and adults in the western world. READ MORE

  2. 7. T Cell Ontogeny and Effector Functions in Galphai2-deficient Colitis

    Author : Malin Bjursten; Göteborgs universitet; []
    Keywords : colitis; T cells; Galphai2- - mice; thymus; pro-inflammatory cytokines; alpha4 integrin;

    Abstract : Inflammatory bowel disease (IBD) comprising Crohn s disease and ulcerative colitis is a disease that affects millions of people worldwide, especially in northern countries such as Sweden, and is characterised by chronic uncontrolled inflammation of the intestinal mucosa. It is the general belief that multiple factors such as genetic and environmental aspects are involved in disease pathogenesis. READ MORE

  3. 8. Obesity-associated inflammation in adipose tissue

    Author : Malin Alvehus; Tommy Olsson; Agneta Holmäng; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; inflammation; pro-inflammatory cytokines; serum; obesity; weight loss; menopause;

    Abstract : Background: Excess body fat, particularly in the visceral depot, is linked to increased mortality and morbidity, including the development of diseases such as type 2 diabetes, cardiovascular disease, and cancer. Chronic low-grade inflammation in adipose tissue may be a key mediator of obesity-associated diseases. READ MORE

  4. 9. Cobalt in the hard metal production industry : exposure via inhalation and skin and the inflammatory response in human keratinocytes

    Author : Maria Klasson; Eva Särndahl; Håkan Westberg; Magnus Lindberg; Alexander Persson; Kristina Jakobsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cobalt; cobalt chloride; skin; HaCaT; in vitro; cell viability; pro-inflammatory cytokines; NLRP3 inflammasome;

    Abstract : Cobalt is a strong sensitizer and can cause contact allergy upon both direct contact or from airborne exposure on the skin. In the skin, keratinocytes are the first cells to come in contact with the metal and will react and respond to the danger by triggering an alarm system resulting in an inflammatory response in the skin. READ MORE

  5. 10. Cellular and molecular responses of periodontal connective tissue cells to Actinobacillus actinomycetemcomitans cytolethal distending toxin

    Author : Georgios N. Belibasakis; Sotirios Kalfas; Ulf H. Lerner; Anders Johansson; Veli-Jukka Uitto; Umeå universitet; []
    Keywords : Medical sciences; Actinobacillus actinomycetemcomitans; cytolethal distending toxin; periodontal connective tissue cells; localized aggressive periodontitis; growth arrest; bone resorption; receptor activator of NF-κB ligand; osteoprotegerin; pro-inflammatory cytokines; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; odontologi; Odontology;

    Abstract : Actinobacillus actinomycetemcomitans is present in elevated proportions and numbers in dental bacterial biofilms of patients with localized aggressive periodontitis. This variant of periodontal disease, occurring in adolescents and young adults, is characterized by rapid and severe destruction of the connective tissues and bone supporting the teeth, eventually culminating in tooth loss. READ MORE