Search for dissertations about: "production of penicillin"

Showing result 1 - 5 of 14 swedish dissertations containing the words production of penicillin.

2. 1. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli

   Author : Marlen Adler; Linus Sandegren; Josep Casadesús; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbapenem; antibiotic resistance; fitness cost; ESBLs; penicillin-binding proteins; gene amplification;

   Abstract : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. READ MORE

4. 2. Microbial Production of Bio-Based Chemicals: A Biorefinery Perspective

   Author : Tarek Dishisha; Bioteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biorefinery; platform chemical; organic acid; propionic acid; 3-hydroxypropionic acid; 3-hydroxypropionaldehyde; methacrylic acid; 1; 3-propanediol; Propionibacterium acidipropionici; Lactobacillus reuteri; Gluconobacter oxydans; high cell density fermentation; biotransformation; product inhibition; cell recycle; immobilized cells; chemical catalysis; pdu operon;

   Abstract : A shift from fossil- to renewable biomass feedstock for the emerging bio-based economy requires the development and adoption of new sustainable technologies that are more suited for transformation of biomass components to chemicals, materials and energy. This thesis presents investigations on the development of processes based on industrial biotechnology as a key element for the production of chemicals from agro-/industrial by-products. READ MORE

5. 3. Bacteriological aspects of treatment failures in streptococcal tonsillitis

   Author : Eva Grahn; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ß-streptococci; treatment failure; a-streptococci; bacterial interference; beta-lactamase; Phenoxymethylpenicillin; penicillin tolerance;

   Abstract : ß-hemolytic streptococci persist in 10-25% of patients with acute streptococal tonsillitis (about 10.000-25.000 per year in Sweden) in spite of treatment with a recommended dosage and schedule of Phenoxymethylpenicillin. READ MORE

6. 4. On metabolic networks and multi-omics integration

   Author : Rasmus Ågren; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; succinate; genome-scale metabolic model; metabolic engineering; systems biology; penicillin; NASH; flux balance analysis; metabolism; cancer; reconstruction;

   Abstract : Cellular metabolism is a highly complex chemical system, involving thousands of interacting metabolites and reactions. The traditional approach to understanding metabolism has been that of reductionism; by isolating and carefully measuring the involved components, the goal has been to understand the whole as the sum of its parts. READ MORE

7. 5. Molecular mechanisms and biological consequences of the production of non-canonical D-amino acids in bacteria

   Author : Alena Aliashkevich; Felipe Cava; Fredrik Almqvist; Andrew J Roe; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; D-amino acids; LD-transpeptidase;

   Abstract : Most bacteria possess a vital net-like macromolecule – peptidoglycan (PG). PG encases bacteria around the cytoplasmic membrane to withstand the high internal turgor pressure and thereby protect the cell from bursting. In addition, PG is a major morphological determinant of bacteria being both required and sufficient to maintain cell shape. READ MORE