Search for dissertations about: "profiling"

Showing result 1 - 5 of 509 swedish dissertations containing the word profiling.

  1. 1. Understanding the Noise Spliceosomal snRNA Profiling

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lei Liu Conze; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ncRNA; snRNA; U1; splice site; alternative splicing; high-throughput sequencing; 454; SNP; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : The concept of the gene has been constantly challenged by new discoveries in the life sciences. Recent challenging observations include the high frequency of alternative splicing events and the common transcription of non-protein-coding-RNAs (ncRNAs) from the genome. The latter has long been considered noise in biological systems. READ MORE

  2. 2. Offender Profiling in Cases of Swedish Stranger Rapes

    University dissertation from Stockholm : Department of Psychology, Stockholm University

    Author : Jelena Corovic; Stockholms universitet.; [2013]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Offender profiling; criminal profiling; stranger rape; serial rapists; prediction; rape themes; crime scene behavior; offender characteristics; situational features; psykologi; Psychology;

    Abstract : Swedish national statistics suggest that the number of reported stranger rapes is steadily increasing. Stranger rape is one of the most difficult types of crime for the police to investigate because there is no natural tie between the victim and offender. READ MORE

  3. 3. Antibody based plasma protein profiling

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Ulrika Qundos; KTH.; KTH.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein profiling; plasma; antibody; affinity proteomics; biomark- ers; multiplex; assay development;

    Abstract : This thesis is about protein profiling in serum and plasma using antibody suspension bead arrays for the analysis of biobanked samples and in the context of prostate cancer biomarker discovery. The influence of sample preparation methods on antibody based protein profiles were investigated (Papers I-III) and a prostate cancer candidate biomarker identified and verified (Papers III-V). READ MORE

  4. 4. High-resolution phenotypic profiling of a eukaryotic ribosome

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Jonathan Esguerra; Göteborgs universitet.; Gothenburg University.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ribosome; ribosomal protein genes; box C D snoRNA; box H ACA snoRNA; 2’-O-ribose methylation; pseudouridylation; high-resolution phenotypic profiling; chemogenetic profiling; Saccharomyces cerevisiae; rRNA modification;

    Abstract : All living cells contain ribosomes, complex macromolecular assemblies of ribonucleic acid (RNA) and proteins, responsible for synthesizing polypeptides in a process called translation. High-resolution three-dimensional ribosomal structures coupled with biochemical studies have paved the way in understanding the various mechanistic events during protein synthesis. READ MORE

  5. 5. MOLECULAR PROFILING OF UROTHELIAL CARCINOMA

    University dissertation from Divison of Clinical Genetics, Lund University

    Author : David Lindgren; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytogenetik; Urology; nephrology; Urologi; nefrologi; Clinical genetics; Klinisk genetik; cytogenetics; Genetics; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; TP53; FGFR3; gene expression profiling; microarray; bladder cancer; urothelial carcinoma; Genetik;

    Abstract : The general aim of this thesis was to molecularly characterize urothelial carcinoma (UC) at the transcriptional level using gene expression microarrays to improve the classification and pathogenetic understanding of this disease. In the first two studies (Articles I and II), gene expression profiling was used to study dysregulated transcriptional networks in a large cohort of UCs. READ MORE