Search for dissertations about: "progenitor cell"

Showing result 1 - 5 of 402 swedish dissertations containing the words progenitor cell.

2. 1. Hematopoietic stem and progenitor cells and potentials for application in fetal cell replacement therapy

   Author : Karina Liuba; Lund Obstetrik och gynekologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in utero hematopoietic cell transplantation; hematopoietic stem cell; multipotent progenitor; fetal therapy; heterotypic cell fusion;

   Abstract : Fetal cell replacement therapy or in utero hematopoietic cell transplantation (IUHCT) is proposed as a non-myeloablative alternative to bone marrow transplantation (BMT) for a number of inborn immunologic, hematologic and metabolic disorders. IUHCT represents the method through which variable amounts of natural or genetically modified hematopoietic cells can be transferred to the fetal recipient in hope of correcting the disorder and preventing postnatal permanent organ damage. READ MORE

4. 2. Genetic pathways controlling CNS development : The role of Notch signaling in regulating daughter cell proliferation in Drosophila

   Author : Caroline Bivik Stadler; Stefan Thor; Jan-Ingvar Jönsson; Allison Bardin; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. READ MORE

5. 3. Genetic mechanisms regulating proliferation and cell specification in the Drosophila embryonic CNS

   Author : Shahrzad Bahrampour; Stefan Thor; Jan-Ingvar Jönsson; Simon Sprecher; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The central nervous system (CNS) consists of an enormous number of cells, and large cellular variance, integrated into an elaborate network. The CNS is the most complex animal organ, and therefore its establishment must be controlled by many different genetic programs. READ MORE

6. 4. Cellular Origin and Development of Glioma

   Author : Nanna Lindberg; Lene Uhrbom; Bengt Westermark; Kristian Pietras; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; brain tumor; PDGF; RCAS TV-A; cell of origin; glial cell; oligodendrocyte progenitor cell; DNA repair; homology-directed repair; RAD51; angiogenesis; histidine-rich glycoprotein; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Molecular Medicine; molekylär medicin genetik och patologi ;

   Abstract : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. READ MORE

7. 5. Identification of Unique Hematopoietic Stem Cell Properties

   Author : Jens Nygren; Lunds universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; Hematologi; extracellulära vätskor; Haematology; extracellular fluids; cell cycle; fusion; transdifferentiation; plasticity; Medicine human and vertebrates ; Medicin människa och djur ; quiescence; hematopoietic stem cell; self-renewal;

   Abstract : Hematopoietic stem cells (HSC) are sufficient and required for life long production of all blood cell lineages. Steady state HSCs are largely quiescent and we demonstrate that the kinetics of HSC cell cycling are slower compared to more committed progenitor cells also during expansion and self-renewal ex vivo and in physiological conditions. READ MORE