Search for dissertations about: "prognostic marker"

Showing result 1 - 5 of 245 swedish dissertations containing the words prognostic marker.

2. 1. Androgen controlled regulatory systems in prostate cancer : potential new therapeutic targets and prognostic markers

   Author : Peter Hammarsten; Anders Bergh; Stina Häggström Rudolfsson; Pernilla Wikström; Sten Nilsson; Umeå universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; prostate cancer; angiogenesis; human biopsy; androgen ablation; castration; prognostic marker; prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; phosphorylated EGFR; phosphorylated epidermal growth factor receptor; Pathology; Patologi;

   Abstract : BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. READ MORE

4. 2. Prognostic and Treatment Predictive Markers Associated with Cyclin D1 Gene Amplification and Epithelial-Mesenchymal Transition in Breast Cancer

   Author : Katja Lundgren; Malmö Patologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; beta-arrestin1; Chk1; Breast Cancer; Tamoxifen; prognostic marker; predictive marker; gene amplification; cyclin D1; EMT; Snail; hypoxia;

   Abstract : Endocrine resistant breast cancer is a major therapeutical challenge and accurate selection of patients susceptible to certain types of anti-hormonal treatment strategies is pivotal. Discovery of novel biomarkers potentially predicting treatment response as well as the clinical course of breast cancer is essential to effectively improve therapies and diagnosis. READ MORE

5. 3. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

   Author : Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

   Abstract : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. READ MORE

6. 4. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

   Author : Marie Klintman; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; predictive marker; resistance; prognostic factor; proliferation; prospective; TIMP-1; Ki67; S-phase; MAI; PPH3; cyclin B1; cyclin A; node-negative; validation;

   Abstract : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. READ MORE

7. 5. Ovarian cancer : Treatment results, prognostic factors, and tumor marker surveillance

   Author : Thomas Högberg; Claes Tropé; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : The total population-based material of 426 ovarian malignancies in the Southeast Health Care Region of Sweden during 1984-1987 was surveyed. It seems that with a program of cytoreductive surgery followed by a cisplatinum chemotherapy combination in the metastasizing cases the overall survival figures have improved. READ MORE