Search for dissertations about: "prolactin receptor"

Showing result 11 - 15 of 32 swedish dissertations containing the words prolactin receptor.

2. 11. Molecular mechanisms of alternative estrogen receptor signaling

   Author : Linda Björnström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Estrogen is a key regulator of growth, differentiation and function in a broad range of target tissues, including the male and female reproductive tracts, mammary gland, bone, brain and the cardiovascular system. The biological effects of estrogen are mediated through estrogen receptor a (ERalpha) and estrogen receptor beta (ERbeta), which belong to a large superfamily of nuclear receptors that act as ligand-activated transcription factors. READ MORE

4. 12. Estrogen receptor signalling in mammary epithelial cells

   Author : Malin Hedengran Faulds; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ER; STAT5; mammary epithelial cell differentiation; EGF; DAX-1;

   Abstract : The mammary gland is a complex tissue going through cycles of extensive proliferation and differentiation. Many hormones are involved in the regulation of development of the mammary gland, including estrogen, prolactin and epidermal growth factor (EGF). READ MORE

5. 13. Myasthenia gravis : clinical aspects and possible involvement of prolactin

   Author : Natalia Tsinzerling; Karolinska Institutet; Karolinska Institutet; []
   Keywords : myasthenia gravis; prolactin; immune regulation; thymic pathology; thymoma; immunosuppressive treatment;

   Abstract : Myasthenia gravis (MG) is an autoimmune disease characterized by the production of antibodies against the skeletal muscle acetylcholine receptor (AChR). MG is usually associated with thymic disorders including thymoma (about 10%) and lymphofollicular hyperplasia (HPL) (up to 80%). READ MORE

6. 14. Population Pharmacodynamic Modeling and Methods for D2-receptor Antagonists

   Author : Klas Petersson; Lena Friberg; Mats Karlsson; An Vermeulen; Robert Bies; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; population modeling; schizophrenia; D2-antagonists; pharmacodynamics; drug development;

   Abstract : Early predictions of a potential drug candidate’s time-course of effect and side-effects, based on models describing drug concentrations, drug effects and disease progression, would be valuable to make drug development more efficient. Pharmacodynamic modeling can incorporate and propagate prior knowledge and be used for simulations of different scenarios. READ MORE

7. 15. Conditions associated with increased growth hormone and prolactin sensitivity

   Author : Amira Said Mohammed Alkharusi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Growth Hormone (GH) and Prolactin (PRL) are critical regulators of body growth and metabolism. Secretion and actions of GH and PRL are regulated at several levels and by different factors. The biological actions of these hormones are initiated by their binding to the respective membrane bound receptors of GH and PRL (GHR and PRLR). READ MORE