Search for dissertations about: "prolactin"

Showing result 1 - 5 of 82 swedish dissertations containing the word prolactin.

  2. 1. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

    Author : Louise Nilsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

    Abstract : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. READ MORE

  4. 2. Molecular characterization of prostate hyperplasia in prolactin transgenic mice

    Author : Karin Dillner; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Prolactin-transgenic; mouse; prolactin; prostate hyperplasia; gene expression analysis;

    Abstract : Benign prostatic hyperplasia (BPH) and prostate cancer are age-related diseases, affecting a majority of elderly men in the western world, and are known to be influenced by several different hormones, including sex hormones. Although the hormone prolactin (PRL) is well known to exert trophic effects on prostate cells, its involvement in the pathophysiology is still poorly characterized. READ MORE

  5. 3. Receptors for growth hormone and prolactin. Regulation and activation

    Author : Gunnel Hellgren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; GH receptor; Janus kinase; GH sensitivity; 5 -untranslated region; prolactin; prolactin receptor adipose tissue; liver; skeletal muscle; epidermal growth factor receptor; tyrosine kinase; kinase activity;

    Abstract : Cytokine receptor activation is dependent on ligand-induced receptor dimerization or oligomerization and subsequent activation of several intracellular proteins. Activation of Janus kinases (Jaks) is probably the first intracellular event that occurs after receptor dimerization. READ MORE

  6. 4. Pleomorphism of prolactin : studies on the hormone purified from human and rat pituitary gland and from urine of pregnant women

    Author : Fred Nyberg; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  7. 5. Prolactin receptor expression and prolactin-mediated effects in adipose tissue

    Author : Charlotte Ling; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : adipose tissue; prolactin receptor; SOCS; leptin; resistin; lipoprotein lipase;

    Abstract : The aim of this study was to investigate the presence of functional prolactin receptors (PRLRs) in white adipose tissue of mice and humans, and the possible functions mediated via PRLRs. In mouse white adipose tissue, three PRLR mRNA isoforms, L-, S2-, and S3-PRLR, and L-PRLR protein expression were detected. READ MORE