Search for dissertations about: "proliferation resistance"

Showing result 1 - 5 of 192 swedish dissertations containing the words proliferation resistance.

  2. 1. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

    Author : Marie Klintman; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; predictive marker; resistance; prognostic factor; proliferation; prospective; TIMP-1; Ki67; S-phase; MAI; PPH3; cyclin B1; cyclin A; node-negative; validation;

    Abstract : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. READ MORE

  4. 2. Invasion and Proliferation in Malignant Cells

    Author : Sofie Svensson Månsson; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; breast cancer; squamous cell carcinoma; basal cell carcinoma; p16; proliferation; invasion; Cytologi; onkologi; cancer;

    Abstract : Two key events in the oncogenic process of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. READ MORE

  5. 3. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer

    Author : Susann Reinbothe; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tamoxifen resistance; proliferation; PI3k pathway; Breast cancer; erythropoietin receptor; estrogen receptor;

    Abstract : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. READ MORE

  6. 4. Cell cycle deregulation in breast cancer subgroups and effects on proliferation, migration and tamoxifen resistance

    Author : Sophie Lehn; Malmö Molekylär patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; subgroups; proliferation; migration; stem cells; tamoxifen; estrogen receptor;

    Abstract : Breast cancer is a heterogenous disease which can be divided in subgroups of distinct biology with disparate prognosis and response to treatment. The overall aim of this thesis was to delineate subgroup specific behaviour in breast cancer cells with focus on proliferation, migration and stem-like cell activity. READ MORE

  7. 5. Proliferation resistances of Generation IV recycling facilities for nuclear fuel

    Author : Matilda Åberg Lindell; Sophie Grape; Ane Håkansson; Staffan Jacobsson Svärd; Roland Carchon; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; safeguards; proliferation resistance; Generation IV; reprocessing; Fysik med inriktning mot tillämpad kärnfysik; Physics with specialization in Applied Nuclear Physics;

    Abstract : The effects of global warming raise demands for reduced CO2 emissions, whereas at the same time the world’s need for energy increases. With the aim to resolve some of the difficulties facing today’s nuclear power, striving for safety, sustainability and waste minimization, a new generation of nuclear energy systems is being pursued: Generation IV. READ MORE