Search for dissertations about: "promoter studies"

Showing result 1 - 5 of 410 swedish dissertations containing the words promoter studies.

  2. 1. Functional Studies on the PDGFR α gene promoter and effects of autocrine PDGF-A stimulation in vivo

    Author : Xiao-Qun Zhang; Hubert Schorle; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Autorcrine PDGF; promoter; PDGFRA; transgenic mice; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Platelet-derived growth factor receptor α (PDGFRα) plays an important role during embryogenesis. After implantation, the patterns of expression of Pdgfrα and its ligand Pdgf-A undergo an "autocrine-paracrine transition", in that Pdgf-A becomes expressed in the ectoderm and epithelia, while Pdgfrα is expressed in the adjacent mesenchymal tissue. READ MORE

  4. 2. Genetic variation and prostate cancer : population-based association studies in Sweden

    Author : Sara Lindström; Henrik Grönberg; Fredrik Wiklund; John Todd; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; epidemiology; SRD5A2; ERG; progression; genetics; association studies; polymorphism; haplotype; CDH1; AR; CYP17; Oncology; Onkologi;

    Abstract : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. READ MORE

  5. 3. Studies of immunoglobulin light chains in rainbow trout (Oncorhynchus mykiss): new insight into the evolution of immunoglobulin genes

    Author : Sirje Timmusk; Greg Warr; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Immunoglobulin genes; gene organization; evolution; comparative immunology; promoter; rainbow trout Oncorhynchus mykiss ; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär immunologi; Molecular Immunology;

    Abstract : In this thesis, the structure and the expression of immunoglobulin (Ig) light chain genes were studied in rainbow trout and including an evolutionary perspective. A novel Ig light chain locus (IgL2) was identified and characterized. READ MORE

  6. 4. Molecular Studies of Three Coliphage Repressor Proteins P2 C, P2 Hy dis C and Wphi C : Kinetics, Oligomeric States and Structural Studies

    Author : Petri Henriksson Peltola; Elisabeth Haggård-Ljungquist; Sankar Adhya; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; molekylärgenetik; Molecular Genetics;

    Abstract : P2, P2 Hy dis and WΦ are heteroimmune and closely related E. coli phages that can either grow lytically or form lysogeny after infection. The developmental switch region that contains two divergent promoters, the early Pe and the lysogenic Pc promoter, and two repressors, controls the life mode of the phage. READ MORE

  7. 5. Studies of Cellular Regulatory Mechanisms : from Genetic Switches to Cell Migration

    Author : Maria Werner; Erik Aurell; Ulrich Gerland; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasma physics; Plasmafysik;

    Abstract : Cellular behaviour depends ultimately on the transcription of genes. If we know how transcription is controlled we have a better chance of understanding cellular processes. This thesis presents six studies, all concerning cellular regulatory mechanisms. One study is purely experimental and five are computational studies. READ MORE