Search for dissertations about: "promyelocytic leukemia"
Showing result 1 - 5 of 17 swedish dissertations containing the words promyelocytic leukemia.
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1. Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry
Abstract : Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features. READ MORE
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2. Characterization of proteins involved in differentiation and apoptosis of human leukemia and epithelial cancer cells
Abstract : Today, cancer is understood as an epigenetic as well as a genetic disease. The main epigenetic hallmarks of the cancer cell are DNA methylation and histone modifications. The latter changes may be an optimal target for novel anticancer agents. READ MORE
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3. The SHB adaptor protein in human and murine leukemia
Abstract : The SHB adaptor protein operates downstream of tyrosine kinase receptors. It has been found previously that Shb deficiency in hematopoietic stem cells (HSCs) results in less proliferation and failure to maintain the myeloid compartment over time. READ MORE
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4. In vitro studies of retinoids and arsenic in non-M3 acute myeloid leukemia
Abstract : Despite advances in the treatment of patients with acute myeloid leukemia (AML), the majority of the patients will die from their disease. The current intensive therapy for AML is also complicated my substantial morbidity and mortality and, as a result, many patients cannot be given the most effective therapy. READ MORE
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5. Molecular alterations and clonal evolution in acute myeloid leukemia : prognostic and therapeutic implications
Abstract : Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic stem cells characterized by inhibition of differentiation, subsequent accumulation of incomplete matured cells at various stages and reduced production of healthy hematopoietic elements. Despite significant progress, the outcome of AML is variable and often suboptimal. READ MORE