Search for dissertations about: "prostaglandin E synthase"

Showing result 11 - 15 of 36 swedish dissertations containing the words prostaglandin E synthase.

  2. 11. Cancer and Inflammation : Role of Macrophages and Monocytes

    Author : Alexander Hedbrant; Jonny Wijkander; Dick Delbro; Ann Erlandsson; Anita Sjölander; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M1 macrophages; M2 macrophages; colon cancer; lung cancer; prostaglandin E2; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE

  4. 12. Apnea and infection in neonates : mediatory role of interleukin-1Beta and prostaglandin E2

    Author : Annika Olsson Hofstetter; Karolinska Institutet; Karolinska Institutet; []
    Keywords : respiration; interleukin-1Beta; prostaglandin E2; newborns; rodents; brainstem;

    Abstract : The breathing pattern of infants, particularly preterm infants, is often irregular or periodic and is frequently interrupted by apnea. The latter represents a major concern in haematology, yet much remains unknown about its incidence, appearance, and pathophysiology. READ MORE

  5. 13. Neonatal respiratory control : inspiration, inflammation and the prostaglandin E2 pathway

    Author : Veronica Siljehav; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Immature or deficient autonomic control is a common problem in infants born at a premature age, and is of central importance in apneas. The pre- and perinatal development of the brainstem neural circuits that control autonomic functions is vital for survival after birth and for the regulation of breathing movements. READ MORE

  6. 14. Talking to the Brain at the Blood-Brain Barrier through Inflammation-Induced Prostaglandin E2

    Author : Ana Maria Vasilache; Camilla Nilsberth; Sivert Lindström; Fredrik Elinder; Ted Ebendal; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The immune-to-brain signaling is a critical survival factor when the body is confronted by pathogens, and in particular by microorganisms. During infections, the ability of the immune system to engage the central nervous system (CNS) in the management of the inflammatory response is just as important as its ability to mount a specific immune response against the pathogen, since the CNS can provide a systemic negative feed-back to the immune activation by release of stress hormones and also can prioritize the usage of the energy resources by the vital organs. READ MORE

  7. 15. Studies of cytokine mediated regulation of central nervous functions : role of prostaglandins

    Author : Monica Ek; Karolinska Institutet; Karolinska Institutet; []
    Keywords : interleukin-1; prostaglandin E2; central nervous system; HPA axis; fever; vagus nerve;

    Abstract : The communication between the immune system and the central nervous system (CNS) results in an array of centrally regulated illness responses, including fever and increased hypothalamus-pituitary-adrenal (HPA) axis activity. The mechanisms by which the immune system signals the brain across the blood-brain barrier have not been completely elucidated, but proinflammatory cytokines, like interleukin-1 (IL-1), are believed to act as important mediators. READ MORE