Search for dissertations about: "prostaglandin"

Showing result 41 - 45 of 208 swedish dissertations containing the word prostaglandin.

  2. 41. Expression of prostaglandin E synthase-1 in periodontitis : in vivo and in vitro studies

    Author : Anna Kats; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Periodontitis is a chronic inflammatory disease characterized by destruction of the supporting structures of the teeth, including gingival tissues and alveolar bone. In advanced cases of periodontitis the ultimate clinical outcome is tooth loss. READ MORE

  4. 42. Talking to the Brain at the Blood-Brain Barrier through Inflammation-Induced Prostaglandin E2

    Author : Ana Maria Vasilache; Camilla Nilsberth; Sivert Lindström; Fredrik Elinder; Ted Ebendal; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The immune-to-brain signaling is a critical survival factor when the body is confronted by pathogens, and in particular by microorganisms. During infections, the ability of the immune system to engage the central nervous system (CNS) in the management of the inflammatory response is just as important as its ability to mount a specific immune response against the pathogen, since the CNS can provide a systemic negative feed-back to the immune activation by release of stress hormones and also can prioritize the usage of the energy resources by the vital organs. READ MORE

  5. 43. Receptor-mediated uterine effects of oxytocin and vasopressin

    Author : Ragner Liedman; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurohypophyseal; vasopressin receptor; oxytocin; pregnancy; oxytocin and vasopressin V1a antagonist; prostaglandin F2 alpha; primary dysmenorrhoea;

    Abstract : The neurohypophyseal hormones oxytocin and vasopressin are important in the regulation of uterine contractility. These hormones, as well as prostaglandin F2α, are most forceful myometrial tissue contractors. READ MORE

  6. 44. Role of prostaglandin E2 as a neuro-immune mediator in the cholinergic anti-inflammatory pathway

    Author : Priya Revathikumar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Therapeutic implications of cholinergic anti-inflammatory pathway (CAP) activation have marked the beginning of a novel treatment strategy of passing electrical impulses along the left vagus nerve to alleviate acute and chronic inflammatory conditions. Extensive work in understanding CAP through vagus nerve stimulation (VNS) have identified key molecular and cellular mechanisms involved in the α7 nicotinic acetylcholine receptor (nAChR) mediated control of inflammation. READ MORE

  7. 45. Catalytic and Structural Properties of Heme-containing Fatty Acid Dioxygenases : Similarities of Fungal Dioxygenases and Cyclooxygenases

    Author : Ulrike Garscha; Ernst Oliw; Per-Johan Jakobsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dioxygenase; prostaglandin H synthase; Gaeumannomyces graminis; Aspergilli; hydroperoxide isomerase; linoleate diol synthase; cytochrome P450; oxylipin; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Abstract : 7,8-Linoleate diol synthase (7,8-LDS) of the take-all pathogen of wheat, Gaeumannomyces graminis, converts linoleic acid to 8R-hydroperoxyoctadecadienoic acid (8-HPODE) by 8-dioxygenase activity (8-DOX), and further isomerizes the hydroperoxide to 7S,8S-dihydroxyoctadecadienoic acid (7,8-DiHODE) by hydroperoxide isomerase activity. Sequence alignment showed homology to prostaglandin H synthase (PGHS), and both enzymes share structural and catalytic properties. READ MORE