Search for dissertations about: "prostanoids"
Showing result 1 - 5 of 21 swedish dissertations containing the word prostanoids.
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1. Prostanoids and colorectal cancer
Abstract : Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. READ MORE
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2. Prostaglandins and angiogenesis in experimental cancer
Abstract : Background and aim. Genes, proteins and pathways have been identified and suggested as potential targets in tumor angiogenesis, but current anti-angiogenic therapies have provided only modest benefits in survival of cancer patients. READ MORE
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3. Methodological studies of eicosanoid enzyme gene expression in vascular endothelium exposed to biomechanical stress
Abstract : Prostaglandins are the major eicosanoids synthesized by vascular endothelial cells, and the vasculature is an important target organ for their bioactive metabolites. In vitro studies have shown that biomechanical forces are important regulators of vascular expression of prostanoid enzymes and release of metabolites. READ MORE
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4. An experimental study of mediators in allergic bronchoconstriction with focus on eicosanoids
Abstract : Mast cells have a central role in the inflammatory response in airways of both atopic and non-atopic asthmatics. The mast cell-derived mediators such as histamine, leukotriene C4 and prostaglandin D2, released upon activation of the cell, produce acute bronchoconstriction that is characteristic of the early asthmatic response (EAR), and contribute to the development of airway inflammation and hyperresponsiveness following the initial reaction. READ MORE
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5. Structure and expression of the TP and EP1 prostanoid receptor genes
Abstract : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. READ MORE