Search for dissertations about: "prostate specific antigen"

Showing result 1 - 5 of 91 swedish dissertations containing the words prostate specific antigen.

  2. 1. Metabolism of free and complexed prostate - specific antigen and their utility for diagnosis and prognosis of prostate cancer

    Author : Thomas Björk; Malmö Urologisk cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benign prostatic hyperplasia; alpha-1-antichymotrypsin; PSA; prostate cancer; prostate-specific antigen; Urology; nephrology; Urologi; nefrologi;

    Abstract : Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). READ MORE

  4. 2. Early diagnosis and treatment of prostate cancer : observational studies in the National Prostate Cancer Register of Sweden and the Västerbotten Intervention Project

    Author : Benny Holmström; Pär Stattin; Håkan Jonsson; Mattias Johansson; Gunnar Aus; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prostate-specific antigen; single nucleotide polymorphism; Urology and andrology; Urologi och andrologi; Urology; kirurgi; särskilt urologi;

    Abstract : Prostate-specific antigen (PSA) testing has caused a steep increase in the incidence of prostate cancer, especially the incidence of localised low risk disease. In order to decrease the overdiagnosis accompanied by PSA testing, analysis of inherited genetic variants have been suggested as potential tools for clinical assessment of disease risk. READ MORE

  5. 3. Characteristics of screen-failures in prostate cancer screening

    Author : Anna Grenabo Bergdahl; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; screening; prostate cancer; screening failures; antigen; age; interval cancer; multiparametric magnetic resonance imaging; non-attendees; prostate cancer screening;

    Abstract : ABSTRACT Although prostate-specific antigen (PSA)-based screening has been shown to reduce prostate cancer (PC)-specific mortality with large variations in mortality reduction with different screening algorithms, the optimal screening strategy has not yet been established. This thesis aims at exploring aspects of underdiagnosis in PC screening, focusing on the impact of screening failures on screening effectiveness. READ MORE

  6. 4. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

    Author : Björn Carlsson; Magnus Essand; Thomas Tötterman; Malcolm Brenner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; Immunology; Immunologi;

    Abstract : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. READ MORE

  7. 5. Prostate Cancer Screening - Aspects of Overdiagnosis

    Author : Rebecka Arnsrud Godtman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; active surveillance; age; cause of death; opportunistic; organized; overdiagnosis; prostate cancer; prostate-specific antigen; risk factors; screening; screening interval;

    Abstract : The overall aim of this thesis is to explore aspects of overdiagnosis, i.e. the diagnosis of a tumor that in the absence of screening would never have been diagnosed, in prostate cancer (PC) screening. READ MORE