Search for dissertations about: "proteases enzymes"

Showing result 1 - 5 of 67 swedish dissertations containing the words proteases enzymes.

2. 1. Chymotrypsin/trypsin-related serine proteases : A structural, functional and evolutionary analysis

   Author : Maryam Poorafshar; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; serine proteases; proteoglycans; mast cells; basophils; Biokemi; Biochemistry; Biokemi; immunologi; Immunology;

   Abstract : Is life possible without proteolytic enzymes? Proteases participate in almost everyaspect of life and they can be found throughout the body and in every cell. Mast cells,together with basophils are, two important effector cells of the immune system. READ MORE

4. 2. Intracellular systems for characterization and engineering of proteases and their substrates

   Author : George Kostallas; Stefan Ståhl; Patrik Samuelson; Matthew DeLisa; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; proteases; flow cytometry; GFP; CAT; protein engineering; ssrA; ClpXP; tobacco etch virus; TEV; site-specific; high-throughput; selection; proteolysis; libraries; Bioengineering; Bioteknik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Abstract : Over the years, the view on proteases as relatively non-specific protein degradation enzymes, mainly involved in food digestion and intracellular protein turnover, has shifted and they are now recognized as key regulators of many biological processes that determine the fate of a cell. Besides their biological role, proteases have emerged as important tools in various biotechnical, industrial and medical applications. READ MORE

5. 3. Studies of Retroviral Reverse Transcriptase and Flaviviral Protease Enzymes as Antiviral Drug Targets : Applications in Antiviral Drug Discovery & Therapy

   Author : Muhammad Junaid; Jarl ES Wikberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virus; enzymes; HIV AIDS; retroviral reverse transcriptase; flaviviral protease; NRTIs; proteochemometrics; drug resistance; DEN; JEV; NS2B H -NS3pro; antiviral; drug targets; drug discovery; drug therapy.; Farmakologi; Pharmacology;

   Abstract : Viruses are a major threat to humans due to their unique adaptability, evolvability and  capability to control their hosts as parasites and genetic elements. HIV/AIDS is the third largest cause of death by infectious diseases in the world, and drug resistance due to the viral mutations is still the leading cause of treatment failure. READ MORE

6. 4. Functional studies of deubiquitinating enzymes

   Author : Bin Zhao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The attachment of ubiquitin to substrate proteins is a key process in regulating cellular events such as cell cycle progression, signal transduction, differentiation, apoptosis, and the clearance of misfolded or aberrant proteins. Like other post-translational modifications, ubiquitination is also reversible. READ MORE

7. 5. Bacterial antibody hydrolyzing enzymes – as bacterial virulence factors and biotechnological tools

   Author : Eleni Bratanis; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunoglobulins; Immunomodulation; Antibody mediated immunity; Glycosylation; Bacterial virulence; Bacterial enzymes; Biotechnology; streptococcus pyogenes; Bdellovibrio bacteriovorus;

   Abstract : Antibodies are an essential part of the human immune system, and antibody mediated immunity has been an area of interest for many researchers for almost a century. An accumulation of knowledge regarding antibody structure, glycosylation and receptor interactions has contributed to the current understanding of antibody mediated immunity. READ MORE