Search for dissertations about: "protection of the brain"

Showing result 1 - 5 of 82 swedish dissertations containing the words protection of the brain.

  1. 1. Ischemic Tolerance and Cell Signaling in the Rat Brain

    Author : Mehrdad Shamloo; Lund Wallenberg Neurocentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preconditioning; cell death; tyrosine phosphorylation; tolerance; ERK; Calpain; CaMKII; PKC; protection; Brain; ischemia; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : A brief period of sublethal ischemia in the brain induces resistance to a subsequent, otherwise lethal ischemic insult. This phenomenon is known as ischemic tolerance or preconditioning. A model of ischemic preconditioning in the rat brain using the two-vessel occlusion model of global cerebral ischemia was established. READ MORE

  2. 2. Intrinsic and extrinsic protection of the brain

    Author : Peter Kimme; Olof Grände; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The brain is a complex organ and critically dependent on its oxygen metabolism and blood supply. The purpose of the present study was twofold: firstly to design, evaluate, and adopt a physiologically stable experimental model for repeated measurements of cerebral cortical microvascular perfusion by a new laser Doppler technique (experimental part (I) - intrinsic model). READ MORE

  3. 3. Cerebral Protection in Experimental Cardiopulmonary Resuscitation : With Special Reference to the Effects of Methylene Blue

    Author : Adriana Miclescu; Lars Wiklund; Samar Basu; Jo Kramer-Johansen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac arrest; cardiopulmonary resuscitation; reperfusion injury; methylene blue; nitric oxide; nitric oxide synthases; blood-brain barrier; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

    Abstract : Although survival rates are increasing, brain injury continues to be a leading cause of death after cardiac arrest (CA). Permanent brain damage after CA is determined by limited tolerance to ischemia from CA and cardiopulmonary resuscitation (CPR), as well as the unique cerebral response to reperfusion after return of spontaneous circulation (ROSC). READ MORE

  4. 4. Influence of intracranial features on brain kinematics during head impact : biomechanical aspects concerning teleological protection of the brain

    Author : Johan Ivarsson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lateral ventricles; impact biomechanics; skull base; brain kinematics; head injury; natural protection;

    Abstract : .... READ MORE

  5. 5. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

    Author : Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

    Abstract : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. READ MORE