Search for dissertations about: "protective immunity"
Showing result 1 - 5 of 163 swedish dissertations containing the words protective immunity.
-
1. Protective Immunity in Atherosclerosis
Abstract : The immune system is a promising target for novel therapies that are aiming at reducing cardiovascular diseases. Autoimmune responses against modified low density lipoprotein (LDL) are believed to promote development of atherosclerosis. Proinflammatory immune responses can be counterbalanced by immunosuppressive regulatory T cells (Tregs). READ MORE
-
2. Malaria : multiclonal infections and protective immunity
Abstract : The mortality and morbidity attributable to malaria remain high in Sub-Saharan Africa, especially among children less than five years of age. In areas of high transmission, immunity to clinical malaria is gradually acquired after repeated exposure to the polymorphic Plasmodium falciparum parasite. READ MORE
-
3. Streptococcal protein Rib and related proteins: a family of repetitive surface proteins that elicit protective immunity
Abstract : ABSTRACT Streptococci constitute a heterogeneous group of Gram-positive bacteria, divided into different serological groups on the basis of antigenic differences in a cell wall-associated carbohydrate. This thesis describes related surface proteins expressed by bacteria in two of these groups, the group B streptococcus (GBS) and the group A streptococcus (GAS). READ MORE
-
4. Mucosal immunity against mycobacterial infection
Abstract : This thesis aimed to the identification of immune biomarkers of mycobacterial infection for better diagnosis of tuberculosis (TB) and also focused on new vaccination strategies with a particular emphasis on the immune responses in the respiratory tract using murine models. Since the lung is the natural habitat for the M. READ MORE
-
5. Infectious immunity and pneumococcal vaccine responses in multiple myeloma and related disorders
Abstract : Multiple myeloma (MM), Waldenstrom’s macroglobulinemia (WM), and monoclonal gammopathy of undetermined significance (MGUS) are B cell conditions associated with suppressed immune functions and susceptibility to infection. Severe pneumococcal disease is common not least in MM patients and vaccination is considered important, although the protective efficacy is debated. READ MORE
