Search for dissertations about: "protein aggregates"
Showing result 1 - 5 of 238 swedish dissertations containing the words protein aggregates.
-
1. Protein Nanomaterials: : Functionalization, Self-assembly, and Applications
Abstract : As one of the major classes of materials that is relevant to biological function of our daily life, proteins are highly interesting in both biological and material science. Self-assembled protein amyloid nanostructures have been considered not only as aggregates in pathological tissue, but also as a kind of advanced one dimension materials in material science perspective due to their favorable characteristics including high aspect ratio, abundant surface charge groups, high stability, and tunable surface properties. READ MORE
-
2. Protein complexes : assembly, structure and function
Abstract : Most proteins must fold into their native conformations to fulfil their biological functions. Failure of proteins to fold leads to cell pathology and a broad range of human diseases referred to as protein misfolding disease, e.g., Alzheimer’s disease, Parkinson’s disease, and type II diabetes. READ MORE
-
3. On aging and the role of Ubp3 in heterochromatic gene silencing and protein quality control
Abstract : Aging is characterized by a build-up of damage in organisms ranging from protists to multi-cellular species. This damage adversely affects core components such as DNA and proteins which are necessary to sustain life. READ MORE
-
4. Protein-surfactant interactions
Abstract : Protein-surfactant interactions in aqueous media have been investigated. The globular proteins lysozyme and bovine serum albumin (BSA) served as model proteins. Several ionic and non-ionic surfactants were used.Fluorescence probe measurements showed that at low sodium dodecyl sulfate (SDS) concentration (< 0. READ MORE
-
5. Fluorescent Probes and Protein Misfolding: Methods and Applications
Abstract : Protein misfolding is a frequently occurring event in living cells and without the quality control, the consequences are disasterous. In this thesis, we studied protein misfolding in vitro by employing a variety of fluorophores, to either detect the highly ordered aggregates of intrinsically disordered proteins/peptides or slight misfolding of a natively folded protein. READ MORE