Search for dissertations about: "protein architecture"

Showing result 1 - 5 of 105 swedish dissertations containing the words protein architecture.

2. 1. The relationship between orthology, protein domain architecture and protein function

   Author : Kristoffer Forslund; Erik Sonnhammer; Cristina Al-Khalili Szigyarto; Sarah Teichmann; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; homology; orthology; paralogy; gene duplications; protein function prediction; low-complexity regions; protein domains; domain architecture evolution; introns; intron position conservation; orthology conjecture; domain grammar hypothesis; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

   Abstract : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. READ MORE

4. 2. Protein-Protein Interactions in Human Aquaporin Regulation

   Author : Jennifer Virginia Roche; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Human Aquaporins; water channels; Protein-protein interaction; Regulation; AQP2; AQP0; LIP5; CaM;

   Abstract : Water is an essential compoment of every living orgamism and forms a major part of the human body. Regulated water transport is crucial for proper cell functioning and body homeostasis. READ MORE

5. 3. Orthology and protein domain architecture evolution

   Author : Volker Hollich; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : A major factor behind protein evolution is the ability of proteins to evolve new domain architectures that encode new functions. Protein domains are widely considered to constitute the "atoms" of protein chains, acting as building blocks of proteins as well as evolutionary units. READ MORE

6. 4. Protein Interactions from the Molecular to the Domain Level

   Author : Patrik Björkholm; Gunnar von Heijne; Dmitrij Frishman; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein interactions; protein domains; membrane proteins; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Abstract : The basic unit of life is the cell, from single-cell bacteria to the largest creatures on the planet. All cells have DNA, which contains the blueprint for proteins. This information is transported in the form of messenger RNA from the genome to ribosomes where proteins are produced. READ MORE

7. 5. Structural and functional properties of transthyretin

   Author : Anders Karlsson; A. Elisabeth Sauer-Eriksson; Salam Al-Karadaghi; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transthyretin; Amyloidosis; X-ray crystallography; Protein structure; Protein; Structural biology; Strukturbiologi;

   Abstract : The hereditary transthyretin (TTR) amyloidoses are rare, and in severe cases, fatal disorders caused by mutations in the TTR gene. The clinical picture is diverse, involving neuropathies and myopathies, and mainly depends on the causative mutation and the sites and rates of amyloid deposition. READ MORE