Search for dissertations about: "protein c"

Showing result 16 - 20 of 1847 swedish dissertations containing the words protein c.

  2. 16. Development of a Method to Measure Plasma Levels of Activated Protein C in Complex with Protein C Inhibitor

    Author : Karin Strandberg; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C inhibitor; activated protein C; hypercoagulability; deep vein thrombosis; Clinical chemistry; myocardial infarction; Klinisk kemi;

    Abstract : Acute myocardial infarction (MI) and deep venous thrombosis (DVT) are conditions caused by thrombus formation with activation of the coagulation system. The plasma concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI), APC–PCI complex is increased in such states. READ MORE

  4. 17. Antithrombotic Effects of Activated Protein C and Heparins in Deep Arterial Injury

    Author : Karl Malm; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; mutagenesis; protein S; protein C; heparin; bleeding; arterial thrombosis; animal model;

    Abstract : The investigations presented in this thesis have evaluated different strategies to prevent thrombosis in an experimental model of deep arterial injury in rats. Unfractionated heparin (UFH) is often used to prevent thrombosis in microvascular surgery and in other vascular interventions, but a major drawback of UFH is increased bleeding. READ MORE

  5. 18. Glial cell line-derived neurotrophic factor : expression patterns, neuronal transport, regulation, effects, and receptor dependence

    Author : Andreas C Tomac; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glial cell line-derived neurotrophic factor GDNF ; neurturin NTN ; persephin PSP ; c Ret proto oncogene Ret ; GPI-linked receptors for the GDNF ligand family GFRas ; transforming growth factor-B TGFB ; Parkinson s disease PD ; dopaminergic DA neurons;

    Abstract : Background: The mammalian nervous system depends upon trophic proteins for survival, growth and adult maintenance. These trophic factors have also been considered as potential therapeutic agents for treating human neurodegenerative disorders. READ MORE

  6. 19. On the behaviour of globular proteins at the solid/liquid interface

    Author : Johan C. Fröberg; KTH; []
    Keywords : ;

    Abstract : Proteins are abundant and in most contexts where they arepresent interfaces of different kinds are found. Interfacesinfluence protein function, and indeed many proteins areincapable of performing their proper functionwithoutthe presence of an interface. READ MORE

  7. 20. Vitamin K-dependent protein S - studies of synthesis, structure and function

    Author : Sofia Somajo; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C4b-binding protein; coagulation; microparticles; protein C; protein S; structure; tissue factor pathway inhibitor;

    Abstract : This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. READ MORE