Search for dissertations about: "protein complexes"

Showing result 1 - 5 of 512 swedish dissertations containing the words protein complexes.

  1. 1. Protein complexes assembly, structure and function

    University dissertation from Umeå : Umeå university

    Author : Kristina Wilhelm; Ludmilla Ludmilla Morozova-Roche; Catharina Svanborg; [2009]
    Keywords : HAMLET; ELOA; lysozyme; amyloid; medicinsk biokemi; Medical Biochemistry;

    Abstract :  Most proteins must fold into their native conformations to fulfil their biological functions. Failure of proteins to fold leads to cell pathology and a broad range of human diseases referred to as protein misfolding disease, e.g., Alzheimer’s disease, Parkinson’s disease, and type II diabetes. READ MORE

  2. 2. Molecular principles of protein stability and protein-protein interactions

    University dissertation from Stockholm : KTH

    Author : Christofer Lendel; Per-Åke Nygren; Christopher M. Dobson; [2005]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; binding thermodynamics; induced fit; molten globule; NMR spectroscopy; protein engineering; protein-protein interactions; protein stability; protein structure.; TECHNOLOGY Bioengineering Structural biochemistry; TEKNIKVETENSKAP Bioteknik Strukturbiokemi;

    Abstract : Proteins with highly specific binding properties constitute the basis for many important applications in biotechnology and medicine. Immunoglobulins have so far been the obvious choice but recent advances in protein engineering have provided several novel constructs that indeed challenge antibodies. READ MORE

  3. 3. Protein - dye complexes : studies on binding and radiation effects

    University dissertation from Stockholm : Stockholm University

    Author : Carl-Gustaf Rosén; [1971]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : .... READ MORE

  4. 4. Structure determination and thermodynamic stabilization of an engineered protein-protein complex

    University dissertation from Stockholm : KTH

    Author : Elisabet Wahlberg; Per-Åke Nygren; Bengt-Harald Jonsson; [2006]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; protein structure; coupled folding; NMR spectroscopy; protein stability; protein-protein interactions; binding thermodynamics; isothermal titration calorimetry; protein engineering; TECHNOLOGY Bioengineering Structural biochemistry; TEKNIKVETENSKAP Bioteknik Strukturbiokemi;

    Abstract : The interaction between two 6 kDa proteins has been investigated. The studied complex of micromolar affinity (Kd) consists of the Z domain derived from staphylococcal protein A and the related protein ZSPA-1, belonging to a group of binding proteins denoted affibody molecules generated via combinatorial engineering of the Z domain. READ MORE

  5. 5. DNA-Mediated Detection and Profiling of Protein Complexes

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Maria Hammond; Ulf Landegren; Masood Kamali-Moghaddam; Christof Niemeyer; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proximity ligation assay; Protein complexes; Protein interactions; Biomarkers; Prions; Antibodies; Medicinsk vetenskap; Medical Science;

    Abstract : Proteins are the effector molecules of life. They are encoded in DNA that is inherited from generation to generation, but most cellular functions are executed by proteins. Proteins rarely act on their own – most actions are carried out through an interplay of tens of proteins and other biomolecules. READ MORE