Search for dissertations about: "protein denaturation"

Showing result 1 - 5 of 51 swedish dissertations containing the words protein denaturation.

  1. 1. Perplexing Protein Puzzles

    Author : Stina Lindman; Biofysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; calbindin D9k; split-GFP; protein G B1; pKa-values; protein reconstitution; Electrostatic interactions; protein stability; protein denaturation; heteronuclear NMR; pH titrations;

    Abstract : Protein structure and stability are inherent in the amino acid sequence and governed by non-covalent interactions. The cooperation between forces is, however, perplexing and not well understood. In order to elucidate and predict protein folding and stability, detailed studies of non-covalent interactions are required. READ MORE

  2. 2. On the mechanism of Urea-induced protein denaturation

    Author : Matteus Lindgren; Per-Olof Westlund; Arnold Maliniak; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Chemical denaturation; Protein unfolding; urea; MD simulations; NMR spectroscopy; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

    Abstract : It is well known that folded proteins in water are destabilized by the addition of urea. When a protein loses its ability to perform its biological activity due to a change in its structure, it is said to denaturate. READ MORE

  3. 3. Protein Misfolding in Human Diseases

    Author : Karin Almstedt; Per Hammarström; Daniel Otzen; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Misfolding; carbonic anhydrase; prion protein; protein stability; Biochemistry; Biokemi;

    Abstract : There are several diseases well known that are due to aberrant protein folding. These types of diseases can be divided into three main categories:Loss-of-function diseasesGain-of-toxic-function diseasesInfectious misfolding diseases Most loss-of-function diseases are caused by aberrant folding of important proteins. READ MORE

  4. 4. The Influence of Salting Procedures on the Characteristics of Heavy Salted Cod

    Author : Kristin Thorainsdottir; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; microstructure; protein; water holding capacity; water; yield; Salting; protein denaturation; cod;

    Abstract : The production of heavy salted cod (bacalao) has changed from being a single-step process salting to a multistep procedure. The aim of this study was to gain a deeper understanding of water retention and yields of heavy salted cod as influenced by salting procedures. READ MORE

  5. 5. Towards First-Principles Understanding of Biomolecular Adsorption

    Author : Svetla Chakarova Käck; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DFT; phenol; adenine; graphite; biomolecules; van der Waals interactions; denaturation; protein; lattice models; PAH dimers; adsorption;

    Abstract : A fundamental understanding of the interactions of biomolecules, such as proteins and DNA, with surfaces is of immense importance in numerous applications and poses a true challenge for theory. Density functional theory (DFT) is a quantum-mechanical tool well established for its ability to balance large system size with good accuracy in first-principles studies. READ MORE