Search for dissertations about: "protein force field"
Showing result 1 - 5 of 40 swedish dissertations containing the words protein force field.
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1. Quantum Chemical Interpretation of Protein Crystal Structure
Abstract : An initial model in the crystallographic structure determination process, usually contains many errors. To produce an accurate model, one must carry out several cycles of crystallographic refinement. READ MORE
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2. Fighting microbial infections with force fields: Evaluating conformational ensembles of intrinsically disordered proteins
Abstract : The main goal of this compilation thesis has been to investigate the conformational ensemble of the intrinsically disordered protein (IDP) histatin 5 by using a mixture of experimental and computational techniques including, but not limited to, small-angle X-ray scattering (SAXS), circular dichroism (CD) spectroscopy, atomistic molecular dynamics (MD) simulations, and coarse-grained Monte Carlo (MC) simulations. Histatin 5 is a peptide of particular interest for two reasons. READ MORE
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3. Assembling a toolkit for computational dissection of dense protein systems
Abstract : The cellular interior is a dense environment. Understanding how such an environment impacts the properties of proteins and other macromolecules, as well as how weak, non-specific interactions drive processes such as protein droplet formation through liquid-liquid phase separation, is a major challenge in biological physics. READ MORE
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4. Bioelectronic Nanosensor Devices for Environmental and Biomedical Analysis
Abstract : A new type of Bioelectronic Nanosensor Device with potential applications in medicine,biotechnology and environmental analysis was designed. The nanosensor is based on RISFET (Regional Ion Sensitive Field Effect Transistor) technology. READ MORE
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5. On the mechanism of Urea-induced protein denaturation
Abstract : It is well known that folded proteins in water are destabilized by the addition of urea. When a protein loses its ability to perform its biological activity due to a change in its structure, it is said to denaturate. READ MORE