Search for dissertations about: "protein function"

Showing result 16 - 20 of 2696 swedish dissertations containing the words protein function.

  2. 16. Vitamin K-dependent protein S - studies of synthesis, structure and function

    Author : Sofia Somajo; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C4b-binding protein; coagulation; microparticles; protein C; protein S; structure; tissue factor pathway inhibitor;

    Abstract : This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. READ MORE

  4. 17. In silico protein design for the enhancement of protein stability and function

    Author : David A. Hueting; Per-Olof Syrén; Hjalmar Brismar; Zbynek Prokop; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein Engineering; Ancestral sequence reconstruction; terpene cyclases; SARS-CoV-2; Spike protein; PET; PETase; rational engineering; Proteinteknik; Förfäders sekvensrekonstruktion; Terpencyklas; SARS-CoV-2; Spike protein; PET; PETas; rationell proteinteknik; Kemi; Chemistry;

    Abstract : Enzymes are natures catalysts that increase the rate of a chemical reaction. The increased rate of a reaction is required to be able to sustain life. Despite the huge impact of enzymes, they are not perfect catalysts. READ MORE

  5. 18. Unlocking protein sequences : Advances in protein structure and ligand-binding site prediction

    Author : Aditi Shenoy; Arne Elofsson; Geoffrey J Barton; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : The protein sequence determines how it will fold into its unique three-dimensional structure. Once folded, proteins perform their functions by interacting with other proteins or molecules called ligands within the cell. Experimental determination of protein structure and function is tedious. READ MORE

  6. 19. Nutrition, exercise and body composition in community-dwelling older adults : Effects on function, wellbeing and mortality

    Author : Åsa von Berens; Tommy Cederholm; Afsaneh Koochek; Margaretha Nydahl; Peter Nordström; Uppsala universitet; []
    Keywords : Older adults; function; nutrition; wellbeing; mortality; exercise; sarcopenic obesity;

    Abstract : Background: The demographic shift in society with more people reaching a high age provides new challenges for both society and the healthcare system.Aim: The overall aim of this thesis was to examine the impact of nutrition, exercise and body composition on function, wellbeing and mortality in community-dwelling older adults. READ MORE

  7. 20. Peripheral nerve function : metabolic features, clinical assessment, and heat shock protein 27

    Author : Kaveh Pourhamidi; Olov Rolandsson; Lars B Dahlin; Svein-Ivar Mellgren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Peripheral neuropathy is a common complication among patients with diabetes mellitus, but whether peripheral neuropathy is present in individuals with impaired glucose tolerance (IGT) is debatable. In order to identify and diagnose peripheral neuropathy correctly, it is important to evaluate diagnostic tools that can be implemented in routine health care to assess both large and small nerve fibre function. READ MORE