Search for dissertations about: "protein kinase C"

Showing result 1 - 5 of 288 swedish dissertations containing the words protein kinase C.

  1. 1. Structure-Function Studies of Enzymes from Ribose Metabolism

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : C. Evalena Andersson; Uppsala universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; activation; isomerase; kinase; potassium; product inhibition; ribose; ribose 5-phosphate; x-ray crystallography; enzyme kinetics; fluorescence spectroscopy; protein structure; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Abstract : In the pentose phosphate pathway, carbohydrates such as glucose and ribose are degraded with production of reductive power and energy. Another important function is to produce essential pentoses, such as ribose 5-phosphate, which later can be used in biosynthesis of nucleic acids and cofactors. READ MORE

  2. 2. Molecular mechanisms underlying morphological effects of protein kinase C under normal conditions and cellular stress

    University dissertation from Lund University, Faculty of Medicine

    Author : Lovisa Sunesson; Lunds universitet.; Lund University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; amytrophic lateral sclerosis; PABPC1; IGF2BP3; G3BP2; peripherin; C1 domain; protein-protein-interactions; Protein kinase C; neurite outgrowth;

    Abstract : The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. READ MORE

  3. 3. Beta-amyloid, tau-protein and cystatin C in the pathophysiology of Alzheimer´s disease

    University dissertation from Divison of Clinical Chemistry and Pharmacology, Lund University

    Author : Maj-Linda Selenica; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neuropsykologi; neurofysiologi; neuropsychology; neurophysiology; Neurology; Medicine human and vertebrates ; Medicin människa och djur ; Clinical chemistry; Klinisk kemi; Kinase inhibitors; Tau protein; Cystatin C; Glycogen Synthase Kinase; Alzheimers Disease; Amyloid beta;

    Abstract : Alzheimer´s Disease (AD) is a progressive neurodegenerative dementia characterized by the extracellular accumulation of the beta-amyloid (Ab) peptide into plaques and intracellular phosphorylation and accumulation of tau protein into neurofibrillary tangles (NFT). Inflammation due to astrocytic and microglial activation is one of the ongoing processes in the disease giving rise to cytokine production and oxidative stress. READ MORE

  4. 4. Localisation of Protein Kinase C in Apoptosis and Neurite Outgrowth

    University dissertation from Division of Molecular Medicine, Department of Laboratory Medicine, UMAS, Malmö

    Author : Anna Schultz; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; Medicine human and vertebrates ; Medicin människa och djur ; Cytology; oncology; cancerology; Cytologi; Prostate Cancer; Neuroblastoma; Ceramide; Golgi Apparatus; Neurite outgrowth; Apoptosis; Protein Kinase C; C1 domain;

    Abstract : Protein kinase C (PKC) is a family of serine/threonine kinases, which are subgrouped into classical (a, bI, bII, g), novel (d, e, h, q) and atypical (z, i/l) isoforms. One major aim of this thesis work was to investigate if altered levels of PKC isoforms influence the apoptotic responses of malignant cell-lines. READ MORE

  5. 5. Roles of protein kinase C in cell death and breast cancer

    University dissertation from Tumour Cell Biology, Department of Laboratory Medicine

    Author : Louise Cornmark; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; protein kinase C; apoptosis; cell death; Smac; Smac mimetics; IAP; stanniocalcin-1;

    Abstract : Popular Abstract in Swedish För att cellerna i kroppen ska fungera krävs det att proteinerna i cellerna beter sig som de ska, dvs att de signalerar på ett korrekt sätt. Det finns en mängd olika signalvägar i en cell och lika många olika mekanismer som styr signalvägarna. READ MORE