Search for dissertations about: "protein mutation"
Showing result 21 - 25 of 598 swedish dissertations containing the words protein mutation.
-
21. The effect of sequence truncation and amino-acid substitutions on the biophysical properties of protein S and calbindin D9k
Abstract : Protein S is a modular protein and a cofactor in the protein C anticoagulant system. It consists of a Gla-module, a thrombin-sensitive loop, four EGF-modules and a SHBG-like module. READ MORE
-
22. The paralemmin protein family : Phosphoproteins involved in filopodia and dendritic spine formation
Abstract : Dendritic spines, which connect neurons with each other, constitute most of the excitatory synapses and undergo experience-dependent neuronal plasticity. The function of dendritic spines and their synaptic strength are highly correlated with morphological changes. READ MORE
-
23. Structure-Function Relationships of Pi Class Glutathione Transferase Studied by Protein Engineering
Abstract : The glutathione transferases (GSTs) represent a superfamily of dimeric proteins involved in cellular detoxication by catalyzing the nucleophilic addition of the reduced glutathione (GSH) to the hydrophobic electrophiles. The present work focuses on the functional role of the conserved structures of GSTP1-1. READ MORE
-
24. New Diagnostic and Therapeutic Approaches in Adrenocortical Cancer
Abstract : Adrenocortical cancer (ACC) is a rare disease that is often difficult to diagnose, and therefore often presents at an advanced stage. Various cytotoxic treatments have been tried with little success. Evaluation of new diagnostic methods and improvement of medical therapies are therefore crucial. READ MORE
-
25. PROTEIN FOLD SWITCHING IN COARSE-GRAINED MODELS
Abstract : Proteins carry out the instructions encoded in genes and are crucial for many important tasks in the living organism. Often the specific three dimensional structure, or fold, of a protein enables it to carry out a given task. READ MORE