Search for dissertations about: "protein networks"

Showing result 1 - 5 of 203 swedish dissertations containing the words protein networks.

2. 1. Functional association networks for disease gene prediction

   Author : Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Abstract : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. READ MORE

4. 2. Global functional association network inference and crosstalk analysis for pathway annotation

   Author : Christoph Ogris; Erik Sonnhammer; Alfonso Valencia; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; biological networks; genome wide functional association networks; global gene association networks; gene networks; protein networks; functional association; functional coupling; network biology pathway analysis; pathway annotation; pathway enrichment; network-based enrichment; enrichment; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Abstract : Cell functions are steered by complex interactions of gene products, like forming a temporary or stable complex, altering gene expression or catalyzing a reaction. Mapping these interactions is the key in understanding biological processes and therefore is the focus of numerous experiments and studies. READ MORE

5. 3. Structures in complex systems : Playing dice with networks and books

   Author : Sebastian Bernhardsson; Petter Minnhagen; Stefan Bornholdt; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Complex systems; networks; statistical physics; biological networks; quantitative linguistics; word frequencies.; Physics; Fysik;

   Abstract : Complex systems are neither perfectly regular nor completely random. They consist of a multitude of players who, in many cases, playtogether in a way that makes their combined strength greater than the sum of their individual achievements. READ MORE

6. 4. Phase Phenomena in Polymer Networks : Empirical Studies on the Influence of Hydrophobicity, Charge Density and Crosslinks on Macroion-Induced Phase Transitions in Polyelectrolyte Gels

   Author : Martin Andersson; Per Hansson; Lennart Piculell; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gel; microgel; microsphere; polystyrenesulfonate; polyacrylate; polyacrylicacid; DoTAB; DoTAC; CTAB; CTAC; network; polyelectrolyte; complex salt; self assembly; phase behaviour; hysteresis; thermodynamic; core-shell; lysozyme; cytochrome c; microscopy; micromanipulator; elastomer; elastic; protein; surfactant; phase behaviour; sorting; PHARMACY; FARMACI; Physical chemistry; Fysikalisk kemi;

   Abstract : The thesis concerns polyelectrolyte gels in contact with oppositely charged proteins and surfactant micelles, and includes of four papers (I-IV). In paper I confocal Raman spectroscopy was introduced as a method to trace micelles and investigate the structure of gel-surfactant complexes, in phase separated gel spheres. READ MORE

7. 5. Gene Regulatory Networks: Dynamics and Stability

   Author : Carl Troein; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; systems; control; Datalogi; numerisk analys; system; kontroll; Computer science; numerical analysis; Fysik; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Physics; medical informatics; transcriptional regulation; gene regulatory networks; Bioinformatics; signaling pathway profiling; stem cell regulation; metabolic pathway; fitness; nested canalyzing rules; Kauffman networks; random Boolean networks; Fysicumarkivet:2007:Troein;

   Abstract : Life as we know it is based on cells that use proteins and RNA to carry out metabolism, self-replication, and other essential tasks. The genes that code for these molecules are encoded in DNA, and through the processes of transcription and translation the cell expresses its genes. READ MORE