Search for dissertations about: "protein secondary structure characterization"

Showing result 16 - 20 of 25 swedish dissertations containing the words protein secondary structure characterization.

2. 16. Molecular characterization of the Ro52 autoantigen and its disease related epitopes

   Author : Lars Ottosson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Ro52; Sjögren s syndrome; autoantibodies; congenital heart block; molecular characterization; TRIM; RBCC; Zn2 ;

   Abstract : The presence of high titers of autoantibodies in patient sera is characteristic for the autoimmune disorder Sjögren s syndrome. The major targets for these autoantibodies are three intracellular proteins Ro52, Ro60 and La. It is still unclear why these proteins become targets for the immune system, and how this autoreactivity is triggered. READ MORE

4. 17. Housing Aquaporins in Nanostructured Glass

   Author : Simon Isaksson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Membrane protein; Water; Interface; Aquaporin; Silica; Formation; Silicification;

   Abstract : Proteins are a group of biomolecules that perform versatile tasks, which in many cases are essential for life. The magnitude of their importance is perhaps expressed by the word protein itself, coined by the Swedish chemist Jöns Jacob Berzelius in the summer of 1838. READ MORE

5. 18. Protein Dynamics Studied by NMR Spin Relaxation. Conformational Transitions of a Calmodulin Mutant

   Author : Patrik Lundström; Biofysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molekylär biofysik; Molecular biophysics; spin relaxation; rotating-frame; NMR; multiple-quantum; EF-hand; chemical shift; chemical exchange; calcium binding proteins; calmodulin;

   Abstract : Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. READ MORE

6. 19. Biochemical Studies of Semenogelins with Emphasis on Zinc-Binding Properties

   Author : Magnus Jonsson; Malmö Klinisk kemi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sexualitet; sexuality; Obstetrik; gynekologi; andrologi; reproduction; andrology; gynaecology; Obstetrics; Klinisk kemi; Clinical chemistry; gel-forming proteins; surface plasmon resonance; prostate-specific antigen; protein C inhibitor; seminal plasma; zinc; semen; semenogelin; reproduktion;

   Abstract : Semenogelins I and II (SgI and SgII) are homologous and rapidly evolving proteins that have a repetitive primary structure and are synthesized mainly in the seminal vesicles. Upon ejaculation, a gelatinous coagulum is formed when the semenogelin-rich secretion from the seminal vesicles is mixed with the prostate secretion, which contains high concentrations of zinc(II) and proteases. READ MORE

7. 20. Intrinsically Disordered Domains of the B Cell Receptor Cell-Free Expression and Characterization by NMR

   Author : Linnéa Isaksson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap;

   Abstract : After the last twenty years of research, the occurrence of flexible proteins without a fixed three-dimensional structure are no longer considered to be rare exceptions from the structure-function paradigm. Instead, intrinsically disordered proteins (IDPs) have become one of the most interesting subjects of modern protein research. READ MORE