Search for dissertations about: "protein stability"

Showing result 11 - 15 of 586 swedish dissertations containing the words protein stability.

  2. 11. To Fold or To Fibrillate? Serendipity in Stability Studies

    Author : Olga Szczepankiewicz; Biofysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein stability; protein reconstitution; protein aggregation; Monellin; PGB1; Split-GFP; Amyloid beta;

    Abstract : Proteins are complex structures and years of research have been spent on attempts to understand their complexity. The non-covalent interactions involved in protein folding are: hydrophobic effect, electrostatic interactions, van der Waals interactions and hydrogen bonding. READ MORE

  4. 12. Diffusive interactions play an important role in protein stability and mobility : Investigations of the intracellular milieu using in-cell NMR

    Author : Therese Sörensen; Mikael Oliveberg; Per Jemth; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; in-cell NMR; protein-protein interactions; mobility; stability; thermodynamics; Nuclear Magnetic Resonance; stopped-flow spectroscopy; proteins; SOD1; HAH1; TTHA1718; cells; cytoplasm; humans; bacteria; ions; polyions; electrostatics; biokemi; Biochemistry;

    Abstract : Proteins are crucial for all cellular life. Every signal received by a cell, and every response to it, is mediated by proteins. Inside cells, these proteins diffusively sample each other’s surfaces, as they travel through the cytoplasm in search of their specific interaction partners. READ MORE

  5. 13. Protein Nanomaterials: : Functionalization, Self-assembly, and Applications

    Author : Lei Wang; Niclas Solin; Olle Inganäs; German Salazar-Alvarez; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : As one of the major classes of materials that is relevant to biological function of our daily life, proteins are highly interesting in both biological and material science. Self-assembled protein amyloid nanostructures have been considered not only as aggregates in pathological tissue, but also as a kind of advanced one dimension materials in material science perspective due to their favorable characteristics including high aspect ratio, abundant surface charge groups, high stability, and tunable surface properties. READ MORE

  6. 14. Protein Misfolding in Human Diseases

    Author : Karin Almstedt; Per Hammarström; Daniel Otzen; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Misfolding; carbonic anhydrase; prion protein; protein stability; Biochemistry; Biokemi;

    Abstract : There are several diseases well known that are due to aberrant protein folding. These types of diseases can be divided into three main categories:Loss-of-function diseasesGain-of-toxic-function diseasesInfectious misfolding diseases Most loss-of-function diseases are caused by aberrant folding of important proteins. READ MORE

  7. 15. Protein folding studies of human superoxide dismutase and ALS associated mutants

    Author : Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. READ MORE